DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13604 and pfkfb4b

DIOPT Version :9

Sequence 1:	NP_001262894.1	Gene:	CG13604 / 42840	FlyBaseID:	FBgn0039137	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	XP_005166082.1	Gene:	pfkfb4b / 386663	ZFINID:	ZDB-GENE-031031-4	Length:	485	Species:	Danio rerio

Alignment Length:	247	Identity:	59/247 - (23%)
Similarity:	87/247 - (35%)	Gaps:	88/247 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 HAKNRKIYIMRHGERVDFTFGTWIPYCFDEFGNYMRKDLNMPKTLPRRKNSPEGWQNDSPLTNVG 552
            |...|.||:.||||                      .|||:...:          ..||.|::.|
Zfish   262 HITPRSIYLCRHGE----------------------SDLNVRGRI----------GGDSGLSHRG 294

  Fly   553 VYQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQKIKLEPGLFEWMAWYPSGV 617
            ...|:.:|:.:.:..::...|:.|...|.|||..|.                           ||
Zfish   295 KEFAHSLGRFIQDQNIKDLKVWTSQMKRTIQTAESL---------------------------GV 332

  Fly   618 P--DWLTKNELTEAKFDVDLDYEPVQP--ASELTARLK----------ESTEQFYERNHDVILQL 668
            |  .|...||: :|....::.||.:|.  ..|...|.:          ||.|...:|...||::|
Zfish   333 PYEQWKALNEI-DAGVCEEMMYEEIQEHYPQEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMEL 396

  Fly   669 LEQTTGNILVVAHATTLDTCSRQLTGGVPRSTNELRQVIHKIPY--CSLATV 718
            ..|.  |:||:.|...: .|  .|...:.:|.:||       ||  |.|.||
Zfish   397 ERQE--NVLVICHQAVM-RC--LLAYFLDKSADEL-------PYLKCPLHTV 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13604	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725
		His_Phos_1	494..728	CDD:278716	57/241 (24%)
pfkfb4b	XP_005166082.1	6PF2K	51..265	CDD:279872	1/2 (50%)
		AAA_33	57..211	CDD:290396
		His_Phos_1	268..451	CDD:278716	57/241 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810