Protein Alignment Epp and Pfrx

DIOPT Version :10

• Sequence 1: NP_001262894.1
• Gene: Epp / 42840
• FlyBaseID: FBgn0039137
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_477451.1
• Gene: Pfrx / 32938
• FlyBaseID: FBgn0027621
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 704
• Identity: 130/704 - (18%)
• Similarity: 220/704 - (31%)
• Gaps: 237/704 - (33%)

  Fly   138 TGALLDRPLKLEPYMSQNFMGFFVAEEDANYLKRLALQYVKEVSNSIISDTYEQLDAIVACFPWC 202
            |..||.||:   |..|..|...:  .:|.......|.......|:|..|.:.....|..|.....
  Fly   101 TPTLLPRPV---PPSSTRFTSSY--NDDLCTCSNCAYSSFSSSSSSASSTSSSSTSATAAGTALA 160

  Fly   203 GAVSSG-TRCIPRS--SRSISLEPHVKSLHLTLAYQFPQAQFNALKALVETLDASCASNWELRLY 264
            .|.:|. .:.:.||  :.||...|:..|..|       :.:..:|..|.:|.|.:..:  ||.:.
  Fly   161 SAAASAVAKKLARSVTATSIMDMPYNTSPSL-------RVRTTSLNQLKKTADLAIEN--ELHVC 216

  Fly   265 SRDPRLATKQVQKVVYPHN---------------------PHETDELELRIGDYIYLNTEVVDSS 308
               |.:.:::::|::.|.:                     ||....:.|......:::.::
  Fly   217 ---PSVMSEELRKLLPPTSETVMTKPFPIRGERTIADCTTPHVIAMVGLPARGKTFISKKL---- 274

  Fly   309 SDGWAEGISWLTGSTGHLPVNYTERTAESDAWTLHRVVQLSKSVASS-----------------L 356
                |..::|:..||....:....|.| :.|:..|...:.....|.:                 |
  Fly   275 ----ARYLNWIGISTRVFNLGEYRRHA-TTAYKSHEFFRADNEEAMAIRNRCANQALHDSCDWLL 334

  Fly   357 TSAEDLDIVDGRSISTEPDDRQNTAHPDIIEGSSFE--------ESEQSVEKYLRQTLKPCLELP 413
            :....:.:.|..: ||.  ||:...|..:::...|.        :..|.:|:.:.:     :::.
  Fly   335 SGQGSIAVFDATN-STR--DRRQLIHDIVVKQHGFRLFFVESICDDPQIIEQNILE-----VKVS 391

  Fly   414 SVQLLNSHNLTHQHNPNTPTIEITTNMSSSSTSMSKQPVDEILVEPPAAQPPRPDDTLSVHSDHS 478
            |...||.         ||..:...............||:||:           .:..||....::
  Fly   392 SPDYLNM---------NTELVVRDFLQRIEHYEERYQPIDEV-----------TESHLSFMKVYN 436

  Fly   479 L--------HPGSLDAS--------HAKNRKIYIMRHGERVDFTFGTWIPYCFDEFGNYMRKDLN 527
            .        :.|.:::.        |...|.||:.||||                      .:.|
  Fly   437 AGKKVVVYNNEGHVESRIVYYLMNIHITPRTIYLTRHGE----------------------SEYN 479

  Fly   528 MPKTLPRRKNSPEGWQNDSPLTNVGVYQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGL 592
            :...:          ..||.|:..|...||.:...:  ||.|||
  Fly   480 LSGLI----------GGDSNLSARGHQYANALSTFI--AQQQID--------------------- 511

  Fly   593 KLTGKQKIKLEPGLFEWMAWYPSGVPD----------WLTKNELTEAKFDVDLDYEPVQP--ASE 645
                        ||..|.:|....:..          |...||: :|....::.||.::.  ..|
  Fly   512 ------------GLRVWTSWMKRAIQTVADVKAPQERWKALNEI-DAGHCEEMTYEQIKEKFPEE 563

  Fly   646 LTAR----------LKESTEQFYERNHDVILQLLEQTTGNILVVAH--------ATTLDTCSRQL 692
            ..||          ..||.|....|...||::|..|  ||:|||:|        |..||..:.:|
  Fly   564 FKARDVNKFAYRYPRGESYEDLVARLEPVIMELERQ--GNVLVVSHQAVLRCLFAYFLDKSADEL 626

  Fly   693 TGGVPRSTNELRQVIHKIPYCSLATVEQVDGVWKLVEPECLPV----THSKNPR 742
                |.....|..||...|......||.:.          ||:    ||...|:
  Fly   627 ----PYLYVPLHTVIKLTPVAYGCKVEHIK----------LPIDAVDTHRPKPK 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Epp	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725	9/78 (12%)
		PhoE	492..728	CDD:440175	57/265 (22%)
Pfrx	NP_477451.1	6PF2K	254..465	CDD:396253	35/247 (14%)
		His_Phos_1	468..651	CDD:459751	56/256 (22%)