Protein Alignment Epp and Pfkfb2

DIOPT Version :10

• Sequence 1: NP_001262894.1
• Gene: Epp / 42840
• FlyBaseID: FBgn0039137
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_001355772.1
• Gene: Pfkfb2 / 18640
• MGIID: 107815
• Length: 533
• Species: Mus musculus
• Alignment Length: 272
• Identity: 69/272 - (25%)
• Similarity: 102/272 - (37%)
• Gaps: 86/272 - (31%)

  Fly   488 HAKNRKIYIMRHGERVDFTFGTWIPYCFDEFGNYMRKDLNMPKTLPRRKNSPEGWQNDSPLTNVG 552
            |...|.||:.||||              .|| |.:.|                 ...||.|:..|
Mouse   248 HVHPRTIYLCRHGE--------------SEF-NLLGK-----------------IGGDSGLSVRG 280

  Fly   553 VYQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQ-KIKLEPGLFEWMAWYPSG 616
            ...|:.:.:.|.|.::|...|:.|...|.|||.    |.|.:|.:| ||..|         ..:|
Mouse   281 KQFAHALKKFLEEQEIQDLKVWTSQLKRTIQTA----ESLGVTYEQWKILNE---------IDAG 332

  Fly   617 VPDWLTKNELTEAKFDVDL---DYEPV---QPASELTARLKESTEQFYERNHDVILQLLEQTTGN 675
            |.:.:|.:|: |.::..:.   |.|..   .|..       ||.:...:|...||::|..|  ||
Mouse   333 VCEEMTYSEI-EQRYPEEFALRDQEKYLYRYPGG-------ESYQDLVQRLEPVIMELERQ--GN 387

  Fly   676 ILVVAHATTLDTCSRQLTGGVPRSTNE---LRQVIH------KIPY-CSLATVE-QVDGVWKLVE 729
            |||::|...: .|  .|...:.:..:|   ||..:|      .:.| |.:.|:. .||.|
Mouse   388 ILVISHQAVM-RC--LLAYFLDKGADELPYLRCPLHIIFKLTPVAYGCKVETITLNVDAV----- 444

  Fly   730 PECLPVTHSKNP 741
                 .||...|
Mouse   445 -----DTHRDKP 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Epp	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725
		PhoE	492..728	CDD:440175	65/253 (26%)
Pfkfb2	NP_001355772.1	6PF2K	30..251	CDD:396253	1/2 (50%)
		His_Phos_1	254..420	CDD:459751	57/223 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	447..492		2/5 (40%)