DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13604 and F09C12.8

DIOPT Version :9

Sequence 1:	NP_001262894.1	Gene:	CG13604 / 42840	FlyBaseID:	FBgn0039137	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_494948.2	Gene:	F09C12.8 / 173881	WormBaseID:	WBGene00017279	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	92/278 - (33%)
Similarity:	130/278 - (46%)	Gaps:	35/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 HSDHSL---HPGSLDASHAKNRKIYIMRHGERVDFTFGTWIPYCFDEFGNYMRKDLNMPKTLPRR 535
            |.|.|.   ||..:   :.....:.:|||.||||.....||..|..| |.|...|||||..||.:
Worm    28 HRDSSRRAHHPNEI---YVSPTVMMVMRHSERVDDCCPGWIEKCNKE-GKYEPFDLNMPTRLPIQ 88

  Fly   536 KNSPEGWQNDSPLTNVGVYQANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTG-KQK 599
            :...: :..|:.:|..|...|.:||:.||......|.:|||||.|||||.|...|   ::| |..
Worm    89 RPLKD-YTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVRE---MSGSKAL 149

  Fly   600 IKLEPGLFEWMAWYPSGVPDWLTKNELTEAKFDVDLDYEPVQPASELTARLKESTEQFYERNHDV 664
            :::|||||| ...||.|||.::  ::|....|.||..:.|......:..  |:.|...|.....:
Worm   150 LRVEPGLFE-NFHYPHGVPRFI--SQLQRHVFPVDKTFRPFLSLETVVG--KQETNDEYNARIQL 209

  Fly   665 ILQLLEQTTG--------NILVVAHATTLDTCSRQLTGGVPRS--TNELRQVIHKIPYCSLATVE 719
            ||..:...:.        .:||||||:|:| .:..|...|||.  ..||..:...:||||||.::
Worm   210 ILNAIADQSEVSTVEKELKVLVVAHASTVD-MAVGLLREVPRKIREEELDNIAIPVPYCSLAYLK 273

  Fly   720 QVDGVWKLVEPECLPVTH 737
            :....|       :|..|
Worm   274 KKCNYW-------VPAAH 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13604	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725
		His_Phos_1	494..728	CDD:278716	85/244 (35%)
F09C12.8	NP_494948.2	PGAM	97..238	CDD:214859	50/148 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002396
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16469
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.870