DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13604 and F53B6.7

DIOPT Version :9

Sequence 1:	NP_001262894.1	Gene:	CG13604 / 42840	FlyBaseID:	FBgn0039137	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_492409.2	Gene:	F53B6.7 / 172710	WormBaseID:	WBGene00009962	Length:	316	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	70/316 - (22%)
Similarity:	133/316 - (42%)	Gaps:	59/316 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   437 TTNMSSSSTSMSKQP--VDEILVEPPAAQPPRPDDTLSVHSDHSLHPGSLDASHAKNRKIYIMRH 499
            |:::.:|:.|..::|  .::.|.|             ..|.|   .||       :...|..|.|
Worm    19 TSSIGASTYSSEEKPNAGEKFLTE-------------LAHID---QPG-------RELTIVAMSH 60

  Fly   500 GERVDFTFGTWIPYCFD----EFGNYMRKDLNM-PKTLPRRKNSPEGWQNDSPLTNVGVYQANLI 559
            .|.:...|..|:..|:.    |:..|   |:|| ||.:||   .|..::.|.|||..|...:...
Worm    61 AESMGLIFPNWVRVCYRRGPMEYHPY---DMNMPPKLVPR---PPLHYKFDPPLTERGQIVSETY 119

  Fly   560 GQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQKIKLEPGLFEWMAWYPSGVPDW-LTK 623
            |:.||.|.::...|:|||..:.:||....::||.|: ...|.::|.|..:....|:...:. |:.
Worm   120 GRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGLS-YTTINIDPALLSYRQMLPTNFQEMLLSP 183

  Fly   624 NELTEAKFDVDLDYEPVQ------PASELTARLKESTEQFYERNHDVILQLLEQTTGNILVVAHA 682
            .......:.:::.|.|.|      ...:...|:    :.|:::|    :..:||.  .::|::..
Worm   184 KAFFNMGYPINIQYLPSQGFIRAENIEDYNLRI----QAFFKKN----IAKIEQK--QVVVISDN 238

  Fly   683 TTLDTCSRQLTGGVPRSTNELRQVIHKIPYCSLATVEQVDGVWKLVEPECLPVTHS 738
            ..:|....:..    .:.:::.|.|.| |.|.:..:....|..::::...||:|.|
Worm   239 VMVDLTRNEHV----ETVDDILQCIKK-PTCQMNFISLKKGEAQIMDSPILPLTKS 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13604	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725
		His_Phos_1	494..728	CDD:278716	56/245 (23%)
F53B6.7	NP_492409.2	PhoE	105..>236	CDD:223483	32/141 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002396
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16469
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870