DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13604 and Y18H1A.4

DIOPT Version :9

Sequence 1:	NP_001262894.1	Gene:	CG13604 / 42840	FlyBaseID:	FBgn0039137	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_490770.1	Gene:	Y18H1A.4 / 171661	WormBaseID:	WBGene00021210	Length:	220	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	64/236 - (27%)
Similarity:	96/236 - (40%)	Gaps:	54/236 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   492 RKIYIMRHGERVDFTFGTWIPYCFDEFGNYMRKDLNMPKTLPRRKNSPEGWQNDSPLTNV-GVYQ 555
            |||:|:||.||.|.....|                       |:.:..:|..:|:.:.:| |..|
Worm     7 RKIWIVRHAEREDNINRNW-----------------------RKLDGADGLTSDNSMLSVRGRQQ 48

  Fly   556 ANLIGQALLEAQVQIDHVYCSPSYRCIQTCTSALEGLKLTGKQKIKLEPGLFE--WMAWYPSGVP 618
            |.........|  ||.|.:.||..|.|:|.::.:|...:    |:|.:.||.|  ::...|.|.
Worm    49 AKECKNRFENA--QISHTFASPFDRTIETASTIIEDKGM----KVKADGGLCEALYLCDKPPGF- 106

  Fly   619 DWLTKNELTEAKFD-VDLDYEPVQPASELT-ARLKESTEQFYERNHDVILQLLEQTTGNILVVAH 681
             |.| ::|.| ||. |||||.||  .|:.| .|.....:....|....:..:.|:..||:|:|.|
Worm   107 -WET-DKLAE-KFPLVDLDYIPV--FSKYTLPREGCGDDACVPRVGKTLRAIFEKYEGNLLLVGH 166

  Fly   682 ATTLDTCSRQLTGGVPRSTNELRQVIHKIPYCSLATVEQVD 722
            ..::..|...|.|              ...|...|||.:.:
Worm   167 GASIGACHEVLMG--------------DFKYVGQATVSEFE 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13604	NP_001262894.1	UBA_UBS3B	23..60	CDD:270486
		SH3_UBASH3	275..333	CDD:212725
		His_Phos_1	494..728	CDD:278716	62/234 (26%)
Y18H1A.4	NP_490770.1	His_Phos_1	9..179	CDD:278716	57/204 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0406
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102745
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710