DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5902 and AMMECR1

DIOPT Version :9

Sequence 1:	NP_001163705.1	Gene:	CG5902 / 42839	FlyBaseID:	FBgn0039136	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_056180.1	Gene:	AMMECR1 / 9949	HGNCID:	467	Length:	333	Species:	Homo sapiens

Alignment Length:	192	Identity:	129/192 - (67%)
Similarity:	153/192 - (79%)	Gaps:	0/192 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 KTVAVPDMCLFCFEVLDCELNNVDGPSVPVFSNDAYPLFVTWKIGRDKRLRGCIGTFSAMELHHG 106
            |.|...:||.|||:||.|.|.....|..|.|:|:.|||||||||||||||||||||||||.||.|
Human   123 KMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSG 187

  Fly   107 LREYALTSAFKDSRFAPISRDELPRLTVSVSILQNFEEAQGHLDWQLGVHGIRIEFLTERGCKRT 171
            ||||.||||.|||||.|::|||||||..|||:|.|||:...:|||::|||||||||:.|:|.|||
Human   188 LREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVCDYLDWEVGVHGIRIEFINEKGSKRT 252

  Fly   172 ATYLPQVATEQGWDQLQTIDSLLRKGGYRAAITPETRKSIKLTRYRSQEIQMHYKEYREYQE 233
            |||||:||.|||||.:||||||||||||:|.||.|.||:||||||||:::.:.|.||..:::
Human   253 ATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFRKTIKLTRYRSEKMTLSYAEYLAHRQ 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5902	NP_001163705.1	AMMECR1	50..219	CDD:280112	122/168 (73%)
AMMECR1	NP_056180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..39
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..120
		AMMECR1	132..301	CDD:396443	122/168 (73%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149646
Domainoid	1	1.000	255	1.000	Domainoid score	I2051
eggNOG	1	0.900	-	-		E1_COG2078
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68944
Inparanoid	1	1.050	273	1.000	Inparanoid score	I2996
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1274811at2759
OrthoFinder	1	1.000	-	-		FOG0002708
OrthoInspector	1	1.000	-	-		oto88739
orthoMCL	1	0.900	-	-		OOG6_101067
Panther	1	1.100	-	-	LDO	PTHR13016
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1929
SonicParanoid	1	1.000	-	-		X1811
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790