Protein Alignment CG31140 and PKC1

DIOPT Version :10

• Sequence 1: NP_001262893.1
• Gene: CG31140 / 42836
• FlyBaseID: FBgn0051140
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_009445.2
• Gene: PKC1 / 852169
• SGDID: S000000201
• Length: 1151
• Species: Saccharomyces cerevisiae
• Alignment Length: 594
• Identity: 113/594 - (19%)
• Similarity: 191/594 - (32%)
• Gaps: 196/594 - (32%)

  Fly     5 GHSFVKKTFHKPTYCHHCSDLLWGLIQQGYICEVCNFIIHERCVSSVVTPCSGIAPCIIKNPVAH 69
            ||.||:|:|:....|.:|.|.   |...|:.|:.|.|:.|::|.::|||.|
Yeast   414 GHHFVQKSFYNIMCCAYCGDF---LRYTGFQCQDCKFLCHKKCYTNVVTKC-------------- 461

  Fly    70 CWSEPTHHKRKFCTVCRKRLDETPAVHCLVCEYFAHIECQDFAVPDCTENATYVPGKELLNVKHQ 134
                          :.:...|..                               |.:..||.:..
Yeast   462 --------------IAKTSTDTD-------------------------------PDEAKLNHRIP 481

  Fly   135 HHWREGNLPSTSKCAYCKKTCWSSECLTGY----------RCEWCGMTTHAGCRMYLPTECNFGI 189
            |.:    ||:::     :.|.|...|  ||          :|..||:..||.|...:|..|...:
Yeast   482 HRF----LPTSN-----RGTKWCCHC--GYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSM 535

  Fly   190 LQPIYLPPHSVSIPRTEVPIEAIIGVQVKSKTSLVRDYSCPSPDLSCPIPGAGSGSLTSLGLKEL 254
                            |:..:.:..:|...:....:..:.||..|...| |..:||  .|...:|
Yeast   536 ----------------EMANKILKTIQDTKRNQEKKKRTVPSAQLGSSI-GTANGS--DLSPSKL 581

  Fly   255 LELHRQRLEQSKQHFLLSTPPTPTSCGSISLCHSPTPSSLTVGETSNEAEQDRERD-----QDQP 314
            .|.....|           ||.|..       |..|||...||..|...:.|...|     |...
Yeast   582 AERANAPL-----------PPQPRK-------HDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHG 628

  Fly   315 EEEPEEENTEQDSALQLTTSTSNVIGNLQKWPSANSSLHLLYTNLFRKLGQGKRRRKRGISSGGL 379
            .|:..:...|.::.|..|........               :::..:.|.....||..|::...:
Yeast   629 REKLNKFIDENEAYLNFTEGAQQTAE---------------FSSPEKTLDPTSNRRSLGLTDLSI 678

  Fly   380 SPS---EDEDDVDGGVCDI--------------SGGDLSDD--YDHCDVALRRRSLRSRQPRDVS 425
            ..|   |.:||:.....::              ..|::.:|  .||.|:..::: |......|..
Yeast   679 EHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQK-LDWENKNDFR 742

  Fly   426 ETDYHGDAEAEAEGETVP-RESCYETSDTGGELTNTDDLDSSLNLISNLSYNSSNNSNACNVPGG 489
            |.|...|:.     .|.| |:...||.....:..:.:.|..:::|
Yeast   743 EADLTIDST-----HTNPFRDMNSETFQIEQDHASKEVLQETVSL-------------------- 782

  Fly   490 ATAPDARNTA-TTSTTAPGKSGHALSVQGGRQQPKTGALAQIKPKPKPILMPKHKAQGKGGSLSS 553
              ||.:.:.: ||...:|.||..:.|.:..::..|...::    ....:|:   |..|||.....
Yeast   783 --APTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVS----LDNFVLL---KVLGKGNFGKV 838

  Fly   554 PLSNSNSSD 562
            .||.|.::|
Yeast   839 ILSKSKNTD 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1_DGKtheta_typeV_rpt1	5..60	CDD:410353	20/54 (37%)
		C1_DGKtheta_typeV_rpt2	64..120	CDD:410354	1/55 (2%)
		C1_DGKtheta_typeV_rpt3	135..197	CDD:410404	16/71 (23%)
		RA1_DAGK-theta	833..922	CDD:340631
		RA2_DAGK-theta	925..1022	CDD:340481
		DAGKc	1121..1266	CDD:214487
		DAGK_acc	1302..1457	CDD:459866
PKC1	NP_009445.2	HR1_PKC-like_1_fungi	1..72	CDD:212011
		HR1_PKC-like_2_fungi	110..181	CDD:212010
		C2_fungal_Pkc1p	211..319	CDD:176071
		C1_ScPKC1-like_rpt1	413..464	CDD:410372	20/80 (25%)
		C1_ScPKC1-like_rpt2	478..536	CDD:410373	16/84 (19%)
		STKc_PKC	828..1145	CDD:270722	8/20 (40%)