DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31140 and dgkaa

DIOPT Version :9

Sequence 1:	NP_001262893.1	Gene:	CG31140 / 42836	FlyBaseID:	FBgn0051140	Length:	1571	Species:	Drosophila melanogaster
Sequence 2:	XP_005162385.1	Gene:	dgkaa / 724010	ZFINID:	ZDB-GENE-060616-305	Length:	766	Species:	Danio rerio

Alignment Length:	392	Identity:	152/392 - (38%)
Similarity:	216/392 - (55%)	Gaps:	61/392 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1111 SMVPSDVRPLLVFVNVKSGGCQGLELISSFRKLLNPYQVFDLDNGGPLPGYVQPITVFVIRPLIF 1175
            |.:| |.||||||||.||||.||..::..|:.||||.||::|.||||.||
Zfish   412 SPIP-DTRPLLVFVNPKSGGKQGERVLRKFQYLLNPRQVYNLSNGGPGPG--------------- 460

  Fly  1176 DSIISLYVFRQITNYKILVCGGDGTIGWVLQCLDNVGQDSECSSPPCAIVPLGTGNDLARVLCWG 1240
                 |..||.:.||:|||||||||:||:|..:|.......   ||.|::||||||||||.|.||
Zfish   461 -----LSFFRDVPNYRILVCGGDGTVGWILDAIDKANLPVR---PPVAVLPLGTGNDLARCLRWG 517

  Fly  1241 SGYTGGEDPLNLLRDVIEAEEIRLDRWTVVFHPEDKPEEPAMKAPSQTTGGAQNEDNSQIFVMNN 1305
            .|| .|.|...:|:|:..:||..:|||::....||          ||..|     |.....::||
Zfish   518 GGY-DGMDLGRILKDIEVSEEGPMDRWSIQVTLED----------SQERG-----DPVPYEIINN 566

  Fly  1306 YFGIGIDADLCLDFHNAREENPNQFNSRLRNKGYYVKMGLRKIVGRKAVKDLQKELRLEVDGKIV 1370
            ||.||:||.:...||..||::|.:||||::||.:|.:....:.:. .:.|.|::.|.:|..|..:
Zfish   567 YFSIGVDASIAHRFHTMREKHPQKFNSRMKNKLWYFEFATSETIS-ASCKKLKECLTIECCGTQL 630

  Fly  1371 ELP--PVDGIIILNILSWGSGANPWG----PDKDDQ-------------FSTPNHYDGMLEVVGV 1416
            :|.  .::||.||||.|...|:|.||    .|:.||             .|..:..|..|||||:
Zfish   631 DLSSLSLEGIAILNIPSMHGGSNLWGEAKKSDRMDQKLPEVIVDPEILKVSPQDMSDKRLEVVGL 695

  Fly  1417 TGVVHLGQIQSGIRTAMRIAQGGHIKIHLNTDMPVQVDGEPWIQSPGDVVVLKSALKATMLKKTK 1481
            .|.:.:|||.:|:::|:|:|:...|.|.....:|:|:|||||:|.|..:.:.... :|:||...:
Zfish   696 EGAMEMGQIYTGLKSAVRLAKTSQITIRTKKPLPMQIDGEPWMQPPCTIHITHKN-QASMLMGPQ 759

  Fly  1482 SK 1483
            :|
Zfish   760 AK 761

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1	6..55	CDD:237996
		C1	69..116	CDD:197519
		C1_1	135..185	CDD:278556
		RA	833..922	CDD:279168
		UBQ	923..1022	CDD:294102
		RRM_SF	1032..1102	CDD:302621
		DAGKc	1121..1266	CDD:214487	67/144 (47%)
		DAGK_acc	1302..1457	CDD:279003	61/173 (35%)
dgkaa	XP_005162385.1	DAG_kinase_N	12..151	CDD:291199
		EFh	156..225	CDD:238008
		EF-hand_7	157..221	CDD:290234
		C1	247..296	CDD:237996
		C1	312..364	CDD:294036
		LCB5	421..744	CDD:224513	142/362 (39%)
		DAGKc	421..542	CDD:214487	67/144 (47%)
		DAGKa	563..736	CDD:214486	61/173 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275907at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820