DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31140 and LOC567728

DIOPT Version :9

Sequence 1:	NP_001262893.1	Gene:	CG31140 / 42836	FlyBaseID:	FBgn0051140	Length:	1571	Species:	Drosophila melanogaster
Sequence 2:	XP_021334575.1	Gene:	LOC567728 / 567728	-ID:	-	Length:	893	Species:	Danio rerio

Alignment Length:	830	Identity:	223/830 - (26%)
Similarity:	342/830 - (41%)	Gaps:	233/830 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   759 SASKAESGHGPSSGGAGGGGGSGGAGGSSAAGASASAAGGSSGHY------------RPDSGSGH 811
            |...|||..|.:.|        .||..|..:..|:|...|:.||.            :|.:||..
Zfish   137 SRHTAESSAGITPG--------SGATTSPCSSRSSSQRSGTGGHTPRGPHRSPGTQPKPPTGSSS 193

  Fly   812 KSD------KSEKDREKKEKEREEKDIEMIKVFDGNNSFRRQ--------QYRVIIVQRTYTLEQ 862
            .|:      .|...|...|:.:.|          ...|.||.        ..:|:.::.......
Zfish   194 SSNALALSKTSNSPRLSPERNQSE----------NRTSLRRSPSPQKGSPSPQVVFLKDIVCYLS 248

  Fly   863 LLTTALRAFHITRDPQAFYLTDLYAP--AGMEDTPMLDPTPVLN-LVHLEGKRPAIYLRFHDRDR 924
            ||...      |.:.:..::..||..  .|:.|:..||  .::| :||:     |.||.:   |.
Zfish   249 LLERG------TPEDKLEFMFRLYDTDGNGLLDSSELD--RIINQMVHV-----AEYLEW---DS 297

  Fly   925 GHVRVYPGKLQCSMLEDPYVSVPVDNSTVIKDLIRDALDK------FGLQDNQIQDYR------- 976
            ..:|    .:...|:|:  :....|.:..:::.||..:..      .|::.|..:|.:
Zfish   298 TELR----PILKEMMEE--IDYDRDGTVTLEEWIRGGMTTIPLLVLLGMETNVQEDGQHIWKLKH 356

  Fly   977 ---------CSEVLL---DRG---------VTERILSWNERPWDIMKQLGKDSIRQMELMRFYMQ 1020
                     |..:||   .:|         |.||.:|.:..|  .:....|.......:...:|:
Zfish   357 FNKPAYCNYCHTMLLGVRKQGLCCALCKYTVHERCVSKDIAP--CISTYAKSRRHTNAMQHVWME 419

  Fly  1021 ----HKQDPHGPNIALFVGNLPTGLSQRNYEQILNKYVTDENKFIS------------------- 1062
                .|.|....:|..:.|  .|||      ..:...:|..||..|
Zfish   420 GNSSAKCDKCHRSIKCYQG--LTGL------HCVWCQITLHNKCASNMKPECDGGPLRDHTLLPS 476

  Fly  1063 -IGPIYYEYGSVVLTFEDSMKAVRAFYNLRETIIED-----------KKLLVLLLPNIEPSMVPS 1115
             |.|:..:..|.|...|.....        .|..||           :.|.:..||.
Zfish   477 YICPVVLDRHSAVKRGEGESSP--------STSPEDTGQCFKFTGDGQALQITPLPG-------- 525

  Fly  1116 DVRPLLVFVNVKSGGCQGLELISSFRKLLNPYQVFDLDNGGPLPGYVQPITVFVIRPLIFDSIIS 1180
             ..||||.||.||||.||..::..|:.||||.||:.|:.|||:.|
Zfish   526 -THPLLVLVNPKSGGRQGERVLRKFQYLLNPRQVYSLERGGPMAG-------------------- 569

  Fly  1181 LYVFRQITNYKILVCGGDGTIGWVLQCLDNVGQDSECSSPPCAIVPLGTGNDLARVLCWGSGYTG 1245
            |..||.:.::::|.|||||::||:|.|:|..   |....||.||:||||||||||.|.||.||.|
Zfish   570 LNFFRDVPDFRVLACGGDGSVGWILDCIDKA---SFARHPPVAILPLGTGNDLARCLRWGGGYEG 631

  Fly  1246 GEDPLNLLRDVIEAEEIRLDRWTVVFHPEDKPEEPAMKAPSQTTGGAQNEDNSQIFVMNNYFGIG 1310
            | ..:..|||:..:.|:.||||.:...|:||.|:               .|.....::||||.||
Zfish   632 G-SLVKFLRDIEHSTEVLLDRWNIDIVPDDKEEK---------------GDPVPYSIVNNYFSIG 680

  Fly  1311 IDADLCLDFHNAREENPNQFNSRLRNKGYYVKMGLRKIVGRKAVKDLQKELRLEVDGKIVEL--P 1373
            :||.:...||..||::|.:||||::||.:|.:.|..:.:. ...|.|.:.:.:|.||.|::|  .
Zfish   681 VDASIAHRFHLMREKHPEKFNSRMKNKLWYFEFGTTETIS-ATCKKLNETIEVECDGIILDLSST 744

  Fly  1374 PVDGIIILNILSWGSGANPWG---------------PD----------KDDQFSTPNHYDGMLEV 1413
            .::||.:|||.|...|:|.||               |:          |:.:|...:..|.:|||
Zfish   745 SLEGIAVLNIPSMHGGSNLWGETKKRRNYNRMSKKVPERMTGSTVTDAKELKFCVQDLSDQLLEV 809

  Fly  1414 VGVTGVVHLGQIQSGIRTA-MRIAQGGHIKIHLNTDMPVQVDGEPWIQSP 1462
            ||:.|.:.:|||.:|:::| .|:||..::.|..:..:|:|:|||||:|.|
Zfish   810 VGLEGAIEMGQIYTGLKSAGRRLAQCSNVTIRTSRLLPMQIDGEPWMQPP 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1	6..55	CDD:237996
		C1	69..116	CDD:197519
		C1_1	135..185	CDD:278556
		RA	833..922	CDD:279168	19/99 (19%)
		UBQ	923..1022	CDD:294102	21/136 (15%)
		RRM_SF	1032..1102	CDD:302621	17/100 (17%)
		DAGKc	1121..1266	CDD:214487	63/144 (44%)
		DAGK_acc	1302..1457	CDD:279003	61/182 (34%)
LOC567728	XP_021334575.1	DAG_kinase_N	4..93	CDD:316983
		Herpes_BLLF1	<106..>237	CDD:330317	25/117 (21%)
		EFh	258..327	CDD:238008	18/84 (21%)
		C1	350..399	CDD:237996	9/50 (18%)
		C1_1	415..466	CDD:278556	12/58 (21%)
		DAGKc	530..651	CDD:214487	63/144 (44%)
		DAGKa	672..854	CDD:214486	61/182 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910