DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31140 and Dgke

DIOPT Version :9

Sequence 1:	NP_001262893.1	Gene:	CG31140 / 42836	FlyBaseID:	FBgn0051140	Length:	1571	Species:	Drosophila melanogaster
Sequence 2:	NP_062378.1	Gene:	Dgke / 56077	MGIID:	1889276	Length:	564	Species:	Mus musculus

Alignment Length:	353	Identity:	139/353 - (39%)
Similarity:	195/353 - (55%)	Gaps:	41/353 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1119 PLLVFVNVKSGGCQGLELISSFRKLLNPYQVFDLDNGGPLPGYVQPITVFVIRPLIFDSIISLYV 1183
            ||::..|.:||...|..|:..|:.||||.||||:....|            |:.|...:::..|
Mouse   216 PLIILANSRSGTNMGEGLLGEFKILLNPVQVFDVTKTPP------------IKALQLCTLLPYY- 267

  Fly  1184 FRQITNYKILVCGGDGTIGWVLQCLDNV---GQDSECSSPPCAIVPLGTGNDLARVLCWGSGYTG 1245
                 :.::||||||||:||||..:|.:   ||:...  |..|::||||||||:..|.||:||.|
Mouse   268 -----SVRVLVCGGDGTVGWVLDAIDEMKIKGQEKYI--PEVAVLPLGTGNDLSNTLGWGTGYAG 325

  Fly  1246 GEDPLNLLRDVIEAEEIRLDRWTVVFHPEDKPEEPAMKAPSQTTGGAQNEDNSQIFVMNNYFGIG 1310
            ......:||:|:||:.|:||||.|                ..|..|..|....:.|.|||||.:|
Mouse   326 EIPVAQVLRNVMEADGIKLDRWKV----------------QVTNKGYYNLRKPKEFTMNNYFSVG 374

  Fly  1311 IDADLCLDFHNAREENPNQFNSRLRNKGYYVKMGLRKIVGRKAVKDLQKELRLEVDGKIVELPPV 1375
            .||.:.|:||..||:.|:.|:||:.||..|:..|.:..:.::. |||.|::.||:||:.||||.:
Mouse   375 PDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQEC-KDLNKKIELELDGERVELPNL 438

  Fly  1376 DGIIILNILSWGSGANPWGPDKDDQFSTPNHYDGMLEVVGVTGVVHLGQIQSGIRTAMRIAQGGH 1440
            :|||:|||..||.|...|....|:.:....|.||:||:|||.|..|..|||..:....||.|...
Mouse   439 EGIIVLNIGYWGGGCRLWEGMGDETYPLARHDDGLLEIVGVYGSFHCAQIQVKLANPFRIGQAHT 503

  Fly  1441 IKIHLNTD-MPVQVDGEPWIQSPGDVVV 1467
            :::.|... ||:|||||||.|.|..|.:
Mouse   504 VRLTLKCSMMPMQVDGEPWAQGPCTVTI 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1	6..55	CDD:237996
		C1	69..116	CDD:197519
		C1_1	135..185	CDD:278556
		RA	833..922	CDD:279168
		UBQ	923..1022	CDD:294102
		RRM_SF	1032..1102	CDD:302621
		DAGKc	1121..1266	CDD:214487	56/147 (38%)
		DAGK_acc	1302..1457	CDD:279003	67/155 (43%)
Dgke	NP_062378.1	C1_1	58..107	CDD:278556
		C1	122..166	CDD:237996
		TIGR00147	216..526	CDD:161732	137/346 (40%)
		DAGKc	218..346	CDD:214487	56/147 (38%)
		DAGKa	366..521	CDD:214486	67/155 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275907at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920