Protein Alignment CG31140 and Dgkd

DIOPT Version :10

• Sequence 1: NP_001262893.1
• Gene: CG31140 / 42836
• FlyBaseID: FBgn0051140
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: NP_001414381.1
• Gene: Dgkd / 368088
• RGDID: 1563309
• Length: 1220
• Species: Rattus norvegicus
• Alignment Length: 899
• Identity: 203/899 - (22%)
• Similarity: 297/899 - (33%)
• Gaps: 416/899 - (46%)

  Fly   977 CSEVLLDRGVTERILS----------------WNERPWDIMKQLGKDSIRQMELMRFYMQHKQDP 1025
            |.|||  .|||...||                .:...|..:..:|||.|             :|.
  Rat   180 CREVL--SGVTSHGLSCEVCKFKAHKRCAVRATSNCKWTTLASIGKDII-------------EDE 229

  Fly  1026 HGPNIAL----FVGNLPTGLSQRNYEQILNKYVTDENKFISIGPIYYEYGSVVLTFED----SMK 1082
            .|  ||:    ..||||..         ....|.|:.           .|| ||..:|    ..|
  Rat   230 DG--IAMPHQWLEGNLPVS---------AKCIVCDKT-----------CGS-VLRLQDWRCLWCK 271

  Fly  1083 AVRAFYNLRETIIEDKKLLVLLLPNIEPSMV--------------PSDVRPLLVFVNVKSGGCQG 1133
            |: ...:.:|:::....|.:..:..|.|:.:              ||...|||||||.|||..||
  Rat   272 AM-VHTSCKESLVMKCPLGLCKVSVIPPTALNSIDSDGFWKATCPPSCTSPLLVFVNSKSGDNQG 335

  Fly  1134 LELISSFRKLLNPYQVFDLDNGGPLPGYVQPITVFVIRPLIFDSIISLYVFRQITNYKILVCGGD 1198
            ::.:..|::||||.|||||.||||..|                    |.:|::...::|||||||
  Rat   336 VKFLRRFKQLLNPAQVFDLMNGGPHLG--------------------LRLFQKFDTFRILVCGGD 380

  Fly  1199 GTIGWVLQCLDNVGQDSECSSPPCAIVPLGTGNDLARVLCWGSGYTGGEDPLNLLRDVIEAEEIR 1263
            |::||||..:|::....:|.   ..::||||||||||||.|||..........:|..:..|....
  Rat   381 GSVGWVLSEIDSLNLHKQCQ---LGVLPLGTGNDLARVLGWGSACDDDTQLPQILAKLERASTKM 442

  Fly  1264 LDRWTVVFHPEDKPEEPAM---------------------------------------------- 1282
            ||||:|:.:....|.:.:.
  Rat   443 LDRWSVMAYETKLPRQASSSTVTEDCSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVL 507

  Fly  1283 ------------KAPSQTTGGAQN----------------------EDNS--------------- 1298
                        ||..:||..:|.                      :|.|
  Rat   508 CETVKDFVARVGKAYEKTTESSQESEVMAKKCSVLKEKLDSLLKTLDDESQASSSLSNPPPTIAE 572

  Fly  1299 ----------------------------QIF---------------------------------- 1301
                                        |||
  Rat   573 EAEDGDGSGNICSSTGDHLVGSACPSRPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQ 637

  Fly  1302 ----------------------------------------------------------------- 1301
                                                                             
  Rat   638 TQEQQGFVLGLSESEKKDLKTDNRVCTSSAHSESCVVAKGRSHRKASRTPCEKLMSKGLSLGSSA 702

  Fly  1302 --------------------------------------------------------------VMN 1304
                                                                          |||
  Rat   703 SLPPNTGSRDSLPALNTKILYPSVRAGMSGSLPGGSVISRLLINADPFNAEPENLEYYTEKCVMN 767

  Fly  1305 NYFGIGIDADLCLDFHNAREENPNQFNSRLRNKGYYVKMGLRKIVGRKAVKDLQKELRLEVDGKI 1369
            ||||||:||.:.|||:|.|:|:|.:..||.:|..:|..:|.::::.| ..::|::::.||.||:.
  Rat   768 NYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHR-TYRNLEQKVLLECDGRP 831

  Fly  1370 VELPPVDGIIILNILSWGSGANPWGPDK-DDQFSTPNHYDGMLEVVGVTGVVHLGQIQSGIRTAM 1433
            :.||.:.||.:|||.|:..|.|.||..| ||.|:.|:..|.:||||.|     .|.:|..:...:
  Rat   832 IPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV-----FGSMQMAVSRVI 891

  Fly  1434 -----RIAQGGHIKIHLNTD--MPVQVDGEPWIQSPGDVVVLKSALKATM---------LKKTKS 1482
                 ||||...:||.:..|  :|||||||.|||.||.:.::......|:         ||..:.
  Rat   892 KLQHHRIAQCRTVKISILGDEGVPVQVDGEAWIQPPGYIRIVHKNRAQTLTRDRAFENTLKSWED 956

  Fly  1483 KRRLTEPH-----ISPAVLSLSVAQQ----GSGSGSMSVSGSPQSQSQQQLQQQ 1527
            |::...|.     :.|.:||...|.|    |..:||:..|....:||.:.::|:
  Rat   957 KQKCELPRPPSFSLHPEILSEEEATQMDQFGQAAGSLIHSIREIAQSHRDMEQE 1010

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1_DGKtheta_typeV_rpt1	5..60	CDD:410353
		C1_DGKtheta_typeV_rpt2	64..120	CDD:410354
		C1_DGKtheta_typeV_rpt3	135..197	CDD:410404
		RA1_DAGK-theta	833..922	CDD:340631
		RA2_DAGK-theta	925..1022	CDD:340481	14/60 (23%)
		DAGKc	1121..1266	CDD:214487	59/144 (41%)
		DAGK_acc	1302..1457	CDD:459866	67/162 (41%)
Dgkd	NP_001414381.1	None