DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31140 and Dgkb

DIOPT Version :9

Sequence 1:	NP_001262893.1	Gene:	CG31140 / 42836	FlyBaseID:	FBgn0051140	Length:	1571	Species:	Drosophila melanogaster
Sequence 2:	XP_006515130.1	Gene:	Dgkb / 217480	MGIID:	2442474	Length:	803	Species:	Mus musculus

Alignment Length:	412	Identity:	144/412 - (34%)
Similarity:	219/412 - (53%)	Gaps:	80/412 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1113 VPSDVRPLLVFVNVKSGGCQGLELISSFRKLLNPYQVFDLDNGGPLPGYVQPITVFVIRPLIFDS 1177
            ||. ..|||||||.||||.||..:...|:.||||.||:.|...||:||
Mouse   432 VPG-THPLLVFVNPKSGGKQGERIYRKFQYLLNPRQVYSLSGNGPMPG----------------- 478

  Fly  1178 IISLYVFRQITNYKILVCGGDGTIGWVLQCLDNVGQDSECSSPPCAIVPLGTGNDLARVLCWGSG 1242
               |:.||.:.::::|.||||||:||:|.|::..   :....||.||:||||||||||.|.||.|
Mouse   479 ---LHFFRDVPDFRVLACGGDGTVGWILDCIEKA---NVVKHPPVAILPLGTGNDLARCLRWGGG 537

  Fly  1243 YTGGEDPLNLLRDVIEAEEIRLDRWTVVFHPEDKPEEPAMKAPSQTTGGAQNEDNSQIFVMNNYF 1307
            |. ||:.:.:|:|:..:.||.||||.....|.||.|:               .|.....::||||
Mouse   538 YE-GENLMKILKDIESSTEIMLDRWKFEVTPNDKDEK---------------GDPVPYSIINNYF 586

  Fly  1308 GIGIDADLCLDFHNAREENPNQFNSRLRNKGYYVKMGLRKIVGRKAVKDLQKELRLEVDGKIVEL 1372
            .||:||.:...||..||::|.:||||::||.:|.:.|..:... ...|.|.:.:.:|.||..::|
Mouse   587 SIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFS-ATCKKLHESVEIECDGVQIDL 650

  Fly  1373 PPV--DGIIILNILSWGSGANPWGPD-----------------------KDDQFSTPNHYDGMLE 1412
            ..:  :||.||||.|...|:|.||..                       |:.:|::.:..|.:||
Mouse   651 INISLEGIAILNIPSMHGGSNLWGESKKKRSHRRIEKKGSDKRPTLTDAKELKFASQDLSDQLLE 715

  Fly  1413 VVGVTGVVHLGQIQSGIRTA-MRIAQGGHIKIHLNTDMPVQVDGEPWIQSPGDVVVL-------- 1468
            |||:.|.:.:|||.:|:::| .|:||...:.|..:..:|:|:|||||:|:|..:.:.
Mouse   716 VVGLEGAMEMGQIYTGLKSAGRRLAQCSSVVIRTSKSLPMQIDGEPWMQTPCTIKITHKNQAPML 780

  Fly  1469 -----KSALKATMLKKTKSKRR 1485
                 |:.|..:::|:|:::.:
Mouse   781 MGPPPKTGLFCSLIKRTRNRSK 802

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1	6..55	CDD:237996
		C1	69..116	CDD:197519
		C1_1	135..185	CDD:278556
		RA	833..922	CDD:279168
		UBQ	923..1022	CDD:294102
		RRM_SF	1032..1102	CDD:302621
		DAGKc	1121..1266	CDD:214487	63/144 (44%)
		DAGK_acc	1302..1457	CDD:279003	60/180 (33%)
Dgkb	XP_006515130.1	DAG_kinase_N	6..148	CDD:373103
		EFh	152..221	CDD:238008
		C1	244..293	CDD:237996
		C1_1	309..358	CDD:365894
		DAGKc	439..560	CDD:214487	63/144 (44%)
		DAGKa	581..761	CDD:214486	60/180 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810