DRSC - DRSC Integrative Ortholog Prediction Tool

Protein Alignment CG31140 and DGKK

Sequence 1:	NP_001262893.1	Gene:	CG31140 / 42836	FlyBaseID:	FBgn0051140	Length:	1571	Species:	Drosophila melanogaster
Sequence 2:	NP_001013764.1	Gene:	DGKK / 139189	HGNCID:	32395	Length:	1271	Species:	Homo sapiens

Alignment Length:	31	Identity:	8/31 - (25%)
Similarity:	14/31 - (45%)	Gaps:	1/31 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LSASECEVLSAVSVDRYPAGGRTTAGGKNVP 64
            |:...|.:...:.|::. ||......||.:|
Human   165 LTPDACRIHGHLYVNKV-AGNFHITVGKAIP 194

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1_DGKtheta_typeV_rpt1	5..60	CDD:410353	5/25 (20%)
		C1_DGKtheta_typeV_rpt2	64..120	CDD:410354	1/1 (100%)
		C1_DGKtheta_typeV_rpt3	135..197	CDD:410404
		RA1_DAGK-theta	833..922	CDD:340631
		RA2_DAGK-theta	925..1022	CDD:340481
		DAGKc	1121..1266	CDD:214487
		DAGK_acc	1302..1457	CDD:459866
DGKK	NP_001013764.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..160
		33 X 4 AA approximate tandem repeats of E-P-A-P	48..179		2/13 (15%)
		PHA03247	<62..179	CDD:223021	2/13 (15%)
		Trypan_PARP	<123..183	CDD:368653	3/18 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	190..209		3/5 (60%)
		PH_DGK_type2	218..314	CDD:270093
		C1_DGK_typeII_rpt1	324..383	CDD:410350
		C1_DGK_typeII_rpt2	399..452	CDD:410402
		DAGKc	493..615	CDD:214487
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	805..825
		DAGKa	857..1014	CDD:214486
		Required for localization to the plasma membrane. /evidence=ECO:0000269\|PubMed:16210324	1199..1268
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1252..1271
Blue background indicates that the domain is not in the aligned region.