DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31140 and Dgka

DIOPT Version :9

Sequence 1:	NP_001262893.1	Gene:	CG31140 / 42836	FlyBaseID:	FBgn0051140	Length:	1571	Species:	Drosophila melanogaster
Sequence 2:	XP_036011466.1	Gene:	Dgka / 13139	MGIID:	102952	Length:	788	Species:	Mus musculus

Alignment Length:	382	Identity:	138/382 - (36%)
Similarity:	207/382 - (54%)	Gaps:	71/382 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1108 IEPSMVPSDVRPLLVFVNVKSGGCQGLELISSFRKLLNPYQVFDLDNGGPLPGYVQPITVFVIRP 1172
            |||   .|:..|||||:|:||||.||..::..|:.:|||.|||||.: ||.||
Mouse   422 IEP---VSNTHPLLVFINLKSGGKQGQSVLWKFQYILNPRQVFDLKD-GPEPG------------ 470

  Fly  1173 LIFDSIISLYVFRQITNYKILVCGGDGTIGWVLQCLDNVGQDSECSSPPCAIVPLGTGNDLARVL 1237
                    |..|:.:..::|||||||||:||||:.:|..   :..:.||.|::||||||||||.|
Mouse   471 --------LRFFKDVPQFRILVCGGDGTVGWVLETIDKA---NFATVPPVAVLPLGTGNDLARCL 524

  Fly  1238 CWGSGYTGGEDPLNLLRDVIEAEEIRLDRWTVVFHPEDKPEEPAMKAPSQTTGGAQNEDNSQIFV 1302
            .||.||. ||:...:|:|:..::.:.||||.:...|:...|: :...|||              :
Mouse   525 RWGRGYE-GENLRKILKDIELSKVVYLDRWFLEVIPQQNGEK-SDPVPSQ--------------I 573

  Fly  1303 MNNYFGIGIDADLCLDFHNAREENPNQFNSRLRNKGYYVKMGLRKIVGRKAVKDLQKELRLEVDG 1367
            :||||.||:||.:...||..||:.|.:||||::||.:|.:....:.: ....|.|::.:.:|:.|
Mouse   574 INNYFSIGVDASIAHRFHLMREKYPEKFNSRMKNKLWYFEFATSESI-FSTCKKLEESVTVEICG 637

  Fly  1368 KIVELP--PVDGIIILNILSWGSGANPWGPDKDDQFST------------------------PNH 1406
            |:::|.  .::||.:|||.|...|:|.||..|.....|                        |:.
Mouse   638 KLLDLSDLSLEGIAVLNIPSTHGGSNLWGDTKRPHGDTCEINQALGSAAKIITDPDILKTCVPDM 702

  Fly  1407 YDGMLEVVGVTGVVHLGQIQSGIRTA-MRIAQGGHIKIHLNTDMPVQVDGEPWIQSP 1462
            .|..|||||:.|.:.:|||.:.:::| .|:|:...|.......:|:|:|||||:|:|
Mouse   703 SDKRLEVVGIEGAIEMGQIYTRLKSAGHRLAKCSEITFQTTKTLPMQIDGEPWMQAP 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1	6..55	CDD:237996
		C1	69..116	CDD:197519
		C1_1	135..185	CDD:278556
		RA	833..922	CDD:279168
		UBQ	923..1022	CDD:294102
		RRM_SF	1032..1102	CDD:302621
		DAGKc	1121..1266	CDD:214487	62/144 (43%)
		DAGK_acc	1302..1457	CDD:279003	57/181 (31%)
Dgka	XP_036011466.1	DAG_kinase_N	39..169	CDD:405237
		EFh	173..242	CDD:238008
		C1	260..320	CDD:412127
		C1_DGKalpha_rpt2	329..390	CDD:410440
		DAGKc	432..552	CDD:214487	62/144 (43%)
		DAGKa	573..754	CDD:214486	57/181 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810