Protein Alignment CG31140 and LOC1269334

DIOPT Version :10

• Sequence 1: NP_001262893.1
• Gene: CG31140 / 42836
• FlyBaseID: FBgn0051140
• Length: 1571
• Species: Drosophila melanogaster
• Sequence 2: XP_061504622.1
• Gene: LOC1269334 / 1269334
• VectorBaseID: AGAMI1_015130
• Length: 1891
• Species: Anopheles gambiae
• Alignment Length: 1799
• Identity: 360/1799 - (20%)
• Similarity: 567/1799 - (31%)
• Gaps: 617/1799 - (34%)

  Fly     4 GGHSFVKKTFHKPTYCHHCSDLLWGLIQQGYICEVCNFIIHERCVSSVVTPCSGIAPCIIKNPVA 68
            |.|.:...:..:||||:.|.:.|.|:...|..||||...:|:||.:..::.|
Mosquito   152 GHHHWYATSHARPTYCNVCREALSGVTSHGLSCEVCKCKVHKRCAAKAISNC------------- 203

  Fly    69 HCWSEPTHHKRKFCTVCRKRLDETPAVHCLVCEYFAHIECQDFAVPDCTENATYVPGKELL---- 129
                       |:.|:..                                     .||:::
Mosquito   204 -----------KWTTLAS-------------------------------------VGKDIIEDSD 220

  Fly   130 -NVKHQHHWREGNLPSTSKCAYCKKTCWSSECLTGYRCEWCGMTTHAGCRMYLPTECNFGILQPI 193
             |:...|.|.|||||.:|||..|.|||.|...|..:||.||..|.|..||...|..|..|..:..
Mosquito   221 GNIVMPHQWMEGNLPVSSKCLVCDKTCGSVMRLQDWRCLWCRSTVHTACRPQSPNSCPLGPARVS 285

  Fly   194 YLPP---HSVSIPRTEVPIEAIIGVQVKSKTSLVRDYSCPSPDLSCPIPGAGSGSLTSLGLKELL 255
            .:||   ||:.:..                   ..|...|....|..:....|.|..:.|:| .|
Mosquito   286 MVPPTSLHSIGLDE-------------------AWDVCKPHGSFSPLLVFVNSKSGDNQGVK-FL 330

  Fly   256 ELHRQRLEQSKQHFLLSTPPTPTSCG----------SISLCHSPTPSSLTVGETSNEAEQDRERD 310
            ...:|.|..::...|:|:.|   ..|          .|.:|....    :||...:|.:....:.
Mosquito   331 RRFKQLLNPAQVFDLISSGP---GLGLRLFRHFDPFRILICSGDG----SVGWVLSEIDHLNMQK 388

  Fly   311 QDQPEEEPEEENTEQDSALQLTTSTSNVIGNLQKW-PSANSSLHLLYTNLFRKLGQGKRR----- 369
            |.|              ...|...|.|.:..:..| .|.:...||  ..|..:..:...:
Mosquito   389 QCQ--------------IAVLPLGTGNDLARVLGWGSSCDDDAHL--PQLLERYEKASTKMLDRW 437

  Fly   370 ------RKRGISSGG-------------LSPSEDE-------------------------DDVDG 390
                  |..||:|..             ||..||.                         :.|:.
Mosquito   438 SVMVFERDIGIASTRTPKMSISHYPDPLLSQYEDSALWHLQSIVYNEDTQMMIQSTRILCETVND 502

  Fly   391 GVCDISGGDLSDDYDH----CDVALRRRSLRSRQPRDVSETDYHGDAEAEAEGETVPRESCYETS 451
            .:..:.  :.|.:.:.    ||:..::..:.....:| .|...|||.|.....:.:.::|..|..
Mosquito   503 FIARVR--ETSSEEEQLSVKCDILRQKLGMLLDTLKD-EEAGLHGDDELFRTLKEIAQKSASERP 564

  Fly   452 -DTGGELTNTDDLDSSLNLISNLSYNSSNNSNAC----------------------------NVP 487
             ||.....|..|..:|...||.:...|...:..|                            :||
Mosquito   565 IDTKTIEKNEKDKLNSKERISRIDRRSEKEALLCRANSLKRAIHEVVEMSEKIIPYAPQKRLSVP 629

  Fly   488 GG---ATAPDARNTATTS--TTAPGKSGHALSVQGGRQQP--KTGALAQIKPKP----------- 534
            ..   |||..:.|:..||  |..|..:        |...|  .|..|..|.|.|
Mosquito   630 MNTLRATASSSDNSVNTSPATLPPPPT--------GMMSPSVSTSRLTCISPLPDMRRDSMDEHF 686

  Fly   535 -KPILMPKHKAQGKGGSLSSPLSNSNSSDCSSASPSAPATLLQLSPVGRSKSFQESAAITAVSRY 598
             ..:.:|..|....|||                              .||....||..|:::..
Mosquito   687 FSTLNLPVPKQFADGGS------------------------------RRSSGVPESYRISSIEE- 720

  Fly   599 KKYGRGLFQRRRSKRSPKNA-----VGVGGKSNYSLDRLSQNIEITI---------QDEDGNFHP 649
                   .:.......||.|     ..:.|:|..:.|...::.:.|:         .|......|
Mosquito   721 -------LEENSVHTEPKLADRILEPPIEGESEMATDNQGKDQDDTLNQKSTTTTTSDSQSTTAP 778

  Fly   650 YDDNYH----MLAGRLDATDVDDDVGFDDLYLDDRPSGASDDVAFAGDISDGGASSRSR-ASDAS 709
            ||.::.    .:...||.....:.:||       :|        |...|.......:.: ..|..
Mosquito   779 YDFSFESDTKTVKFDLDPNSAFERLGF-------KP--------FKKTIEQHHQQQQQQLGGDGQ 828

  Fly   710 DGHVLGRLLRQVRQGLSVGWRKPRYQKRRARSISEEFSSGDTPRFKDEESASKAESGHGPSSGGA 774
            ..|..|....|. |.:.|      |::...|:.::..                       ..|||
Mosquito   829 SHHTEGGGYLQF-QPIEV------YERNYYRTHAQRL-----------------------GIGGA 863

  Fly   775 GGGGGSGGAGGSSAAGASASA---------------------------------AGGSSGHYRPD 806
            |..|.:||:|.:::|.|.||.                                 ...||....|.
Mosquito   864 GKAGLAGGSGEATSAKAGASCNMLQVPTICIPSLEKPPENIYFSENITIIDTDMPERSSSDEVPG 928

  Fly   807 SGSGHKSDKSEKDREKKEK--EREEKDIEMIKVFDGNNSFRRQQYRVIIVQRTYTLEQLLTTALR 869
            .||...|..|.::.....:  :|:..:...:.|.|........::..|....|..    .|.||.
Mosquito   929 DGSDILSAISNEECSVTSEILDRQSDNNSQVHVGDIIQDLDNDRFSHIDSPETSD----TTEALH 989

  Fly   870 AFHITRDPQAFYLTDLYAPAGMEDTPMLDPTPVLNLVHLEGKRPAIYLRFHDRDRGHVRVYPGKL 934
            ...:..|..:....||.. |..::|...|.|.:..|.|.  ||               |.:..|.
Mosquito   990 GESLMDDISSVLGQDLLG-ALQDNTITEDTTTLCTLEHT--KR---------------RSFKVKR 1036

  Fly   935 QCSMLEDPYVSVPVDNSTVIKDLIRDALDKFGLQDNQIQ-DYRCSEVLLDRGVTERILSWNERPW 998
            ..:...:|.                 .||:.|.::.... |.||.    |:.|.|      .|..
Mosquito  1037 TVAAASEPV-----------------ELDQCGFENRVFDIDNRCD----DQKVKE------PRFC 1074

  Fly   999 DIMKQLGKDSIRQMELMRFYMQHKQDPHGPNIALFVGNLPTGLSQRNYEQILNKYVTDENKFISI 1063
            .:.|.:..:.|.:....|        ||.       |.....|..:.|   .|:....||::.:|
Mosquito  1075 SLAKFVEGNDIARKSFKR--------PHR-------GGAVRNLGPQRY---ANRLSVGENEYENI 1121

  Fly  1064 G-------PIYYEYGSVVLTFEDSMKAVRAFYNLRETIIEDKKLLVLLLPNIEPSMVPSDVRPLL 1121
            .       |::.....|.::..|:         :|.:..|.:||:.......|...:|.|.
Mosquito  1122 KSFARNLLPVHGSPSDVSVSETDT---------VRSSGFEYRKLVSAANAEDEDESLPDDE---- 1173

  Fly  1122 VFVNVKSGGCQGLELISSFRKLLNPYQVF-----------------------DLDNGGPLPG--- 1160
                      .|...:|...:....::..                       |.|....|.|
Mosquito  1174 ----------LGERSLSENEESRPQHRAHADDDEEGEEDDEEEEEEEEEEEEDEDGDESLLGRDD 1228

  Fly  1161 -----------YVQPI--TVFVI----RPLIFDSIISLYV---------------------FRQI 1187
                       :..|.  |:.|:    .|.|.|.:.||.|                     .|:.
Mosquito  1229 EHEKDDRSEKSFQLPCIPTINVVVEPPSPAISDELRSLRVPDIRRHSEHTPNLLAPREIDINRRH 1293

  Fly  1188 TNYKILVCGGDGTIGWVLQCLDNVGQDSECSSPPCAIVPLGTGNDLARVLCWGSGYTGGEDPLNL 1252
            :|....:.|.|......|.|  :.......||......|.|.|:..:.:.....|..|.:.
Mosquito  1294 SNNNPNLLGFDSEHIRFLNC--SPAASRRISSGSLLFKPEGLGSSKSNIFSSNLGLFGTDK---- 1352

  Fly  1253 LRDVIEAEEIRLDRWTVVFHPEDKPE--------EPAMKAPS---QTTGGA-------QNEDN-- 1297
                 :|||.:         .|:|.|        .|.::.||   .:||..       .|.|.
Mosquito  1353 -----DAEERK---------KEEKEERVKKLPIINPLVRLPSWPNVSTGTGFISKCLLANADTLC 1403

  Fly  1298 ---SQIF--------------VMNNYFGIGIDADLCLDFHNAREENPNQFNSRLRNKGYYVKMGL 1345
               |.:.              ||||||||||||.:.|||||.|||:|.:..||.:|..:|..:|.
Mosquito  1404 AAVSPLMDPDETLLEGYYEKAVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRAKNYMWYGVLGS 1468

  Fly  1346 RKIVGRKAVKDLQKELRLEVDGKIVELPPVDGIIILNILSWGSGANPWGPDK-DDQFSTPNHYDG 1409
            ::.: :|..|:|:::::||.||:.:.||.:.||::|||.|:..|.|.||..| ||.|...:..|.
Mosquito  1469 KQWL-QKTYKNLEQKVQLECDGQRIPLPSLQGIVVLNIPSFMGGTNFWGSKKEDDCFLAQSFDDR 1532

  Fly  1410 MLEVVGVTGVVHLGQIQSGIRTAMRIAQGGHIKIHLNTD--MPVQVDGEPWIQSPGDV-VVLKSA 1471
            :||||.|.|.|.:...:.......||||...::|::..:  :|:|||||.|:|.||.: ::.|:.
Mosquito  1533 ILEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGEECVPIQVDGEAWLQPPGMIRIIHKNR 1597

  Fly  1472 LK--------ATMLKKTKSKRR-------------LTEPHISPA 1494
            ::        ...||..:.|:|             .:|.|::|:
Mosquito  1598 VQMLCRNRSLEVSLKSWQEKQRQHSISIAREQPSTASEHHVAPS 1641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31140	NP_001262893.1	C1_DGKtheta_typeV_rpt1	5..60	CDD:410353	17/54 (31%)
		C1_DGKtheta_typeV_rpt2	64..120	CDD:410354	2/55 (4%)
		C1_DGKtheta_typeV_rpt3	135..197	CDD:410404	27/61 (44%)
		RA1_DAGK-theta	833..922	CDD:340631	18/88 (20%)
		RA2_DAGK-theta	925..1022	CDD:340481	16/97 (16%)
		DAGKc	1121..1266	CDD:214487	31/208 (15%)
		DAGK_acc	1302..1457	CDD:459866	67/157 (43%)
LOC1269334	XP_061504622.1	None