DRSC/TRiP Functional Genomics Resources

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Protein Alignment AP-1sigma and AP1S2

DIOPT Version :9

Sequence 1:NP_001247273.1 Gene:AP-1sigma / 42835 FlyBaseID:FBgn0039132 Length:157 Species:Drosophila melanogaster
Sequence 2:NP_001259000.1 Gene:AP1S2 / 8905 HGNCID:560 Length:160 Species:Homo sapiens


Alignment Length:159 Identity:129/159 - (81%)
Similarity:136/159 - (85%) Gaps:4/159 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 MLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLY 66
            |.|||||||||||||||||:...||.|||||||||.|:|||||||||||||:|.|||||||||||
Human     1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLY 65

  Fly    67 FCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNV 131
            ||||||..||||:|||||||||||||||||||||||||||||||||||||.|:|||:||||||||
Human    66 FCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNV 130

  Fly   132 LKAIASQDLLQED----EAVEGTLRDIGL 156
            ||||...||||||    |.....|.:|||
Human   131 LKAIEQADLLQEDAKEAETPRSVLEEIGL 159

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AP-1sigmaNP_001247273.1 AP1_sigma 4..145 CDD:341435 123/144 (85%)
AP1S2NP_001259000.1 AP1_sigma 2..144 CDD:341435 122/141 (87%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165158744
Domainoid 1 1.000 247 1.000 Domainoid score I2158
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H2908
Inparanoid 1 1.050 258 1.000 Inparanoid score I3143
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53551
OrthoDB 1 1.010 - - D1307450at2759
OrthoFinder 1 1.000 - - FOG0000441
OrthoInspector 1 1.000 - - otm41674
orthoMCL 1 0.900 - - OOG6_100926
Panther 1 1.100 - - LDO PTHR11753
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R60
SonicParanoid 1 1.000 - - X298
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1514.900

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