DRSC/TRiP Functional Genomics Resources

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Protein Alignment AP-1sigma and AP1S1

DIOPT Version :9

Sequence 1:NP_001247273.1 Gene:AP-1sigma / 42835 FlyBaseID:FBgn0039132 Length:157 Species:Drosophila melanogaster
Sequence 2:NP_001274.1 Gene:AP1S1 / 1174 HGNCID:559 Length:158 Species:Homo sapiens


Alignment Length:157 Identity:120/157 - (76%)
Similarity:137/157 - (87%) Gaps:1/157 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASL 65
            ||.|||||||||||||||||:|..||.:||:.|||:..:|||||||||||||:|.|:||||||||
Human     1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASL 65

  Fly    66 YFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKN 130
            |||||||..||||:|||:|||||||||||||||||||||||||||||||||.|:||::|:||||:
Human    66 YFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKS 130

  Fly   131 VLKAIASQDLLQ-EDEAVEGTLRDIGL 156
            |||||...|||| |||:....|.::||
Human   131 VLKAIEQADLLQEEDESPRSVLEEMGL 157

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AP-1sigmaNP_001247273.1 AP1_sigma 4..145 CDD:341435 113/141 (80%)
AP1S1NP_001274.1 AP1_sigma 3..145 CDD:341435 112/141 (79%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165158746
Domainoid 1 1.000 247 1.000 Domainoid score I2158
eggNOG 1 0.900 - - E1_COG5030
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 258 1.000 Inparanoid score I3143
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53551
OrthoDB 1 1.010 - - D1307450at2759
OrthoFinder 1 1.000 - - FOG0000441
OrthoInspector 1 1.000 - - otm41674
orthoMCL 1 0.900 - - OOG6_100926
Panther 1 1.100 - - O PTHR11753
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R60
SonicParanoid 1 1.000 - - X298
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1514.800

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