Protein Alignment GluProRS and YHR020W

DIOPT Version :10

• Sequence 1: NP_524471.2
• Gene: GluProRS / 42834
• FlyBaseID: FBgn0005674
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_011884.1
• Gene: YHR020W / 856413
• SGDID: S000001062
• Length: 688
• Species: Saccharomyces cerevisiae
• Alignment Length: 707
• Identity: 326/707 - (46%)
• Similarity: 438/707 - (61%)
• Gaps: 78/707 - (11%)

  Fly  1064 SEKAAKNVID--PEVKTLLALKG-EYKTLSGKDWTP--------DAKSEPAVVKKEASPVSMASP 1117
            ||..||..::  |..::.:|:|. .:|..:.|..||        .:.:.|:.:...|:.......
Yeast     4 SEAFAKLCVNEKPPAESAVAVKSLVFKPKTPKSATPVPIVVVALQSTTTPSALIANATSSKDPRL 68

  Fly  1118 AKDELTQEINAQGEKVRA------AKGNKAAKEVIDAEVA------------------------- 1151
            |:|:|.::. .|.|..||      |........:||.|:.
Yeast    69 ARDDLVKQA-FQSESARAFILGDLANATSNFHLLIDHELGTVDGDTILQLNDSTYMKKSDMMKFL 132

  Fly  1152 -------KLLALKAKYKEVTGTDFPVAGRGGGGGGGSAKKAPKEAQPKPAKPVKKEPAADASGAV 1209
                   |::....:..:.|.|:              .||..|:.||..|...    ||.|:.|:
Yeast   133 NNFEDSQKVVDFSQEVSKETATE--------------GKKQQKKQQPSKAGTA----AAAAAAAL 179

  Fly  1210 KKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYDVSGCYILRQWSFAIWKAIKTWFDAEITRMGV 1274
            :....:|:...|..:.|.||.|::|||||::|||||||||||..|:|||:.|:.|||.:|..:||
Yeast   180 EDAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCYILRPPSYAIWENIQKWFDDKIKAIGV 244

  Fly  1275 KECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKSGDSDLAEPIAVRPTSETVMYPAYAKWVQSYR 1339
            :..|||:|||..||||||.|:..|||||||||::|.|:|.||||:||||||||||.|||||||||
Yeast   245 QNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPYYAKWVQSYR 309

  Fly  1340 DLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAFADKEEAAKEVLDILDLYALVYTHLLAI 1404
            |||::|||||:|||||||.|.||||||||||||||||....::|.:|||.|||.||.||..|||:
Yeast   310 DLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHTAHLTAKDAEEEVLQILDFYAGVYEELLAV 374

  Fly  1405 PVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQGATSHHLGQNFSKMFEIVYEDP--ETQQKKY 1467
            |||||||||||||||||:|||.|.:|..:||.|||||||||||||||||.:..|:|  ....|.:
Yeast   375 PVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFSKMFNLSVENPLGSDHPKIF 439

  Fly  1468 VYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACIQAIVVPCGITVNTKDDERAQLLDACKALEK 1532
            .||||||::||.||||:|:|:||:|||:||.|:..|::|:|.|||..|.:::|..:.:..:::|.
Yeast   440 AYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIPVGITKKTSEEQRKHIHETARSVES 504

  Fly  1533 RLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRLEVGPKDLKAQQLVAVRRDTVEKITIPLADV 1597
            ||...|:|..|||.|||:|||||:.:||||:|:|:|:||||::..|:|.|||:..:|..:...::
Yeast   505 RLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIELGPKDIEKNQVVVVRRNDSKKYVVSFDEL 569

  Fly  1598 EKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTDFCGFLEQKNILLAPFCGEISCEDKIKADSA 1662
            |.:||.:||.:...:..||:|...:|...|..|:.|...|.:||::|||:||.:.||:.||..||
Yeast   570 EARIPEILEEMQGDLFKKAKELFDTHRVIVNEWSGFVPALNKKNVILAPWCGVMECEEDIKESSA 634

  Fly  1663 R---GEEAEPG--APAMGAKSLCIPFDQPAPIAASDKCINPSCTNKPKFYTLFGRSY 1714
            :   |||.|..  ||:|||||||||||||. :....|||  .|......|.:|||||
Yeast   635 KKDDGEEFEEDDKAPSMGAKSLCIPFDQPV-LNEGQKCI--KCERIAVNYCMFGRSY 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluProRS	NP_524471.2	PLN02907	1..715	CDD:215492
		WEPRS_RNA	748..797	CDD:238473
		WHEP-TRS	821..870	CDD:459819
		WEPRS_RNA	894..943	CDD:238473
		WEPRS_RNA	973..1022	CDD:238473
		WEPRS_RNA	1048..1097	CDD:238473	11/43 (26%)
		WEPRS_RNA	1122..1169	CDD:238473	12/84 (14%)
		proS_fam_I	1219..1714	CDD:273062	286/501 (57%)
YHR020W	NP_011884.1	YbaK_like	24..>106	CDD:444658	17/82 (21%)
		proS_fam_I	188..688	CDD:273062	286/502 (57%)