Protein Alignment GluProRS and pars-1

DIOPT Version :10

• Sequence 1: NP_524471.2
• Gene: GluProRS / 42834
• FlyBaseID: FBgn0005674
• Length: 1714
• Species: Drosophila melanogaster
• Sequence 2: NP_001370820.1
• Gene: pars-1 / 176024
• WormBaseID: WBGene00004189
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 604
• Identity: 353/604 - (58%)
• Similarity: 433/604 - (71%)
• Gaps: 34/604 - (5%)

  Fly  1119 KDELTQEINAQGEKVRAAKGNK-----AAKEVIDAEVAKLLALKAKYKEVTGTDFPVAGRGGGGG 1178
            |:|:|:||..||.:||..||:|     |.||.||    ||||||..||||||.::       ...
 Worm     4 KEEITKEIEEQGAEVRRVKGDKNSTEEAKKEAID----KLLALKLTYKEVTGQEY-------AAP 57

  Fly  1179 GGSAKKAPKEAQPKPAKPVKKEPAADASGAVKKQTRLGLEATKEDNLPDWYSQVITKGEMIEYYD 1243
            .....|..||.:|| .:|.::|...|.    ||||.||:...|:||..:|||:||||.|||||||
 Worm    58 NARQSKPKKEEKPK-QQPKQQEKKQDG----KKQTLLGVGTKKDDNYSEWYSEVITKAEMIEYYD 117

  Fly  1244 VSGCYILRQWSFAIWKAIKTWFDAEITRMGVKECYFPIFVSKAVLEKEKTHIADFAPEVAWVTKS 1308
            |||||:||.||||:|::|:.|||:.|.::|||.||||:|||.|.||:||||||||||||||||::
 Worm   118 VSGCYVLRPWSFAVWESIQEWFDSGIKKLGVKNCYFPMFVSNAALEREKTHIADFAPEVAWVTRA 182

  Fly  1309 GDSDLAEPIAVRPTSETVMYPAYAKWVQSYRDLPIRLNQWNNVVRWEFKQPTPFLRTREFLWQEG 1373
            |:|::|||||:||||||||||:|.|||||:|||||:||||.||||||||.|||||||||||||||
 Worm   183 GNSEMAEPIAIRPTSETVMYPSYKKWVQSHRDLPIKLNQWCNVVRWEFKHPTPFLRTREFLWQEG 247

  Fly  1374 HTAFADKEEAAKEVLDILDLYALVYTHLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISASGRAIQ 1438
            |||||:..:|.|||..||||||.|||.|||||||||||:|||||||||:||||||:::.:||.||
 Worm   248 HTAFANPADAEKEVFQILDLYAGVYTDLLAIPVVKGRKSEKEKFAGGDFTTTVEAYVACNGRGIQ 312

  Fly  1439 GATSHHLGQNFSKMFEIVYEDPETQ-QKKYVYQNSWGITTRTIGVMIMVHADNQGLVLPPHVACI 1502
            |||||||||||||||:|.||||..: ::.:.:|||||::|||||.|:|:|.|::||||||.||.:
 Worm   313 GATSHHLGQNFSKMFDISYEDPAKEGERAFAWQNSWGLSTRTIGAMVMIHGDDKGLVLPPRVAAV 377

  Fly  1503 QAIVVPCGITVNTKDDERAQLLDACKALEKRLVGGGVRCEGDYRDNYSPGWKFNHWELKGVPLRL 1567
            |.||||.|.    |.:.:..|.||...:.|.||..||:.|.|.|:||:.|||||||||||||:|.
 Worm   378 QVIVVPVGF----KTENKQSLFDAVDKVTKDLVADGVKAEHDLRENYNAGWKFNHWELKGVPIRF 438

  Fly  1568 EVGPKDLKAQQLVAVRRDTVEKITIPLADVEKKIPALLETIHESMLNKAQEDMTSHTKKVTNWTD 1632
            ||||.||...|:.||.|...||..:.|..:.|.:.:||:.||.:|.||......||.|..|...:
 Worm   439 EVGPNDLAKNQVTAVIRHNGEKKQLSLEGLSKTVKSLLDEIHTAMYNKVLAQRDSHLKSTTCIEE 503

  Fly  1633 FCGFLEQKNILLAPFCGEISCEDKIKADSAR--GEEAEPGAPAMGAKSLCIPFDQPAPIAASDKC 1695
            |...|::|.|:|:||||...||::||..|.|  ||.|:     ||||:||||.|||.....| ||
 Worm   504 FKKLLDEKCIILSPFCGRPDCEEEIKKASTREDGEGAQ-----MGAKTLCIPLDQPKQELPS-KC 562

  Fly  1696 INPSCTNKPKFYTLFGRSY 1714
            :.||||...|.:.||||||
 Worm   563 LFPSCTYNAKAFALFGRSY 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluProRS	NP_524471.2	PLN02907	1..715	CDD:215492
		WEPRS_RNA	748..797	CDD:238473
		WHEP-TRS	821..870	CDD:459819
		WEPRS_RNA	894..943	CDD:238473
		WEPRS_RNA	973..1022	CDD:238473
		WEPRS_RNA	1048..1097	CDD:238473
		WEPRS_RNA	1122..1169	CDD:238473	27/51 (53%)
		proS_fam_I	1219..1714	CDD:273062	308/497 (62%)
pars-1	NP_001370820.1	S15_NS1_EPRS_RNA-bind	14..57	CDD:469733	24/53 (45%)
		proS_fam_I	93..581	CDD:273062	308/497 (62%)