Protein Alignment CG12268 and FAR1

DIOPT Version :9

• Sequence 1: NP_001247272.1
• Gene: CG12268 / 42833
• FlyBaseID: FBgn0039131
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_011518702.1
• Gene: FAR1 / 84188
• HGNCID: 26222
• Length: 518
• Species: Homo sapiens
• Alignment Length: 536
• Identity: 179/536 - (33%)
• Similarity: 285/536 - (53%)
• Gaps: 49/536 - (9%)

  Fly    15 IAKFYANKTILITGATGFMGKVLVEKLLRSCADLNVIYLLIRTKKGVDPSVRKEQYFKCVIFGKL 79
            |.::|..|.:|:||||||:||||:|||||||..:|.:|:|:|.|.|..|..|.|:.....:|.:|
Human     4 IPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSGKLFDRL 68

  Fly    80 LEKNPGIVDKVRVVKGDLLEPDLGLSANDTNTLASNVEVVFHCAANVRFDQPLRPMVMMNVVGTL 144
            .::||...:|:..:..:|.:|.|.||..|...:..:..::|||||.|||::.||..|.:||:.|.
Human    69 RDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLRDAVQLNVIATR 133

  Fly   145 KVLRLAEKMSQLQALVHVSTSYCQCNESVLEERAYPAPQNPFSIIEMVETMDDEALAEITPKLLN 209
            :::.||::|..|:..:||||:|..||...::|..||.|.:|..:|:.:|.|||..:.:|||||:.
Human   134 QLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIG 198

  Fly   210 GLPNTYAYSKALSEDLICRYNNKLPIIITRPSIVTAAIHEPLPGWIEGVNGPTGLMIGAARGVIR 274
            ..||||.|:|||:|.::.:...||.:.|.|||||.|:..||.||||:..|||:||.|.|.:|::|
Human   199 DRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILR 263

  Fly   275 SMHCNPDYASTVIPVDKAINGMILCGYQRGKASQEKGNKQTGVEFCNLCISSKALMSWGD----S 335
            ::..:.:..:.::|||..:|..:...:..|   ..:..:...:...|....|.....||:    .
Human   264 TIRASNNALADLVPVDVVVNMSLAAAWYSG---VNRYMRPRNIMVYNCTTGSTNPFHWGEVEYHV 325

  Fly   336 IETGRRFFYETPLSFALWYPGGSIKKNY--YHHLFCVIFFHYLPAYFIDFWLLVFGQKPFLLNVQ 398
            |.|    |...||..|...|..::..|:  ||:...|  .|..||:..|.:|.:.|:.|.::...
Human   326 IST----FKRNPLEQAFRRPNVNLTSNHLLYHYWIAV--SHKAPAFLYDIYLRMTGRSPRMMKTI 384

  Fly   399 RKVSMGLKLLQYYTTKRWEFRNERFQEMSSQLSLLDQDLFDTSVGQVNWETYISNYIVGMRTYIL 463
            .::...:..|:|:|:..|.:..|....:.:||:..|:..|:..|.|::|..||.||.:|.:.|:|
Human   385 TRLHKAMVFLEYFTSNSWVWNTENVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCLGTKKYVL 449

  Fly   464 GESEDTLPQARKVLRR-----------LYILDW---------VSKVLFF--SLSFWFLWTHLDGF 506
            .|....||.|||.|.:           |.||.|         ...:.:|  ||.:.||
Human   450 NEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFL------- 507

  Fly   507 VERSDAFIRSSLSTIY 522
                 ::.|:|.:..|
Human   508 -----SYFRASSTMRY 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12268	NP_001247272.1	PLN02996	12..463	CDD:215538	159/453 (35%)
		FAR-N_SDR_e	22..347	CDD:187547	124/328 (38%)
		FAR_C	372..463	CDD:176924	25/90 (28%)
FAR1	XP_011518702.1	PLN02996	2..449	CDD:215538	159/453 (35%)
		FAR-N_SDR_e	11..333	CDD:187547	124/328 (38%)
		Sterile	360..450	CDD:281068	25/89 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850