DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12268 and FAR4

DIOPT Version :9

Sequence 1:	NP_001247272.1	Gene:	CG12268 / 42833	FlyBaseID:	FBgn0039131	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_190040.3	Gene:	FAR4 / 823579	AraportID:	AT3G44540	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	126/516 - (24%)
Similarity:	235/516 - (45%)	Gaps:	90/516 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ESDIAKFYANKTILITGATGFMGKVLVEKLLRSCADLNVIYLLIR------TKKGVDPSVRKEQY 70
            :|:..:|..:||||:||..||:.||.|||:||....:..::||:|      ..:.....|.::..
plant     2 DSNCIQFLHDKTILVTGVPGFLAKVFVEKILRIQPKVKKLFLLLRAADNESAMQRFHSEVLEKDL 66

  Fly    71 FKCVIFGKLLEKN--PGIVDKVRVVKGDLLEPDLGLSAND-TNTLASNVEVVFHCAANVRFDQPL 132
            |: |:...|.::|  ..|.:||..:.||:...:||:..:| ...:.:.::::.:.||...||:..
plant    67 FR-VLKNALGDENLKAFITEKVVPIPGDISVDNLGVKGSDLLQHMWNEIDIIVNVAATTNFDERY 130

  Fly   133 RPMVMMNVVGTLKVLRLAEKMSQLQALVHVSTSYCQCNES-VLEERAYPAPQNPFSIIEMVETMD 196
            ...:.:|..|.|.||..|:|..:.|.|:||||:|.:..:| :|.|:.:          .|.||::
plant   131 DVGLSVNTFGPLNVLNFAKKCVKGQLLLHVSTAYVRGEKSGLLHEKTF----------HMGETLN 185

  Fly   197 ---------------------------DEALAEITPKL------LNGLPNTYAYSKALSEDLICR 228
                                       :|.:::....|      |:|.||||.::|::.|.|:..
plant   186 GHRKLVIETEMELMKQKLKELQKQNCSEEEISQSMKDLGMSRAKLHGWPNTYVFTKSMGEMLLGN 250

  Fly   229 YNNKLPIIITRPSIVTAAIHEPLPGWIEGVNGPTGLMIGAARGVIRSMHCNPDYASTVIPVDKAI 293
            |...|||:|.||:::|:...||.||||||:.....:::...:|.::....:|:....:||||...
plant   251 YRENLPIVIIRPTMITSTFSEPFPGWIEGLRTIDSVIVAYGKGRLKCFLADPNSVLDLIPVDMVA 315

  Fly   294 NGMI-LCGYQRGKASQEKGNKQTGVEFCNLCISSKALMSWGDSIETGRRFFYETPL----SFALW 353
            |.|: ......||.     ..||.....:.|   |..:::....:....:|.:.||    ..::.
plant   316 NAMVTAAAIHAGKL-----GSQTVYHVGSSC---KNPITFEQIHDLAASYFTKNPLVRRDGSSIL 372

  Fly   354 YPGGSIKKNYYHHLFCVIFFHYLPAYFIDFWLLVF----GQKPFLLNVQRKVSMGLKLLQYY--- 411
            ...|:|........|.:...:.||...:....:::    |.|  ..::.||:.:.::|:..|
plant   373 VSKGTILSTMAQFSFYMTLRYKLPLQMLRLIYVIYPWWNGNK--YKDIDRKIKLAMRLVDLYRPY 435

  Fly   412 --------TTKRWEFRNERFQEMSSQLSLLDQDLFDTSVGQVNWETYISN-YIVGMRTYIL 463
                    .|...:.|.:| :|::.::    ..||:.....::||.|::. :|.|:.||:|
plant   436 VLFKGIFDDTNTEKLRLKR-KEINKEM----YGLFEFDPKSIDWEDYMTTIHIPGLITYVL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12268	NP_001247272.1	PLN02996	12..463	CDD:215538	125/514 (24%)
		FAR-N_SDR_e	22..347	CDD:187547	97/368 (26%)
		FAR_C	372..463	CDD:176924	21/106 (20%)
FAR4	NP_190040.3	PLN02996	1..492	CDD:215538	126/516 (24%)
		FAR-N_SDR_e	12..362	CDD:187547	97/368 (26%)
		Sterile	393..492	CDD:281068	22/106 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.930