DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12268 and CG34342

DIOPT Version :9

Sequence 1:	NP_001247272.1	Gene:	CG12268 / 42833	FlyBaseID:	FBgn0039131	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	159/495 - (32%)
Similarity:	266/495 - (53%)	Gaps:	9/495 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IAKFYANKTILITGATGFMGKVLVEKLLRSCADLNVIYLLIRTKKGVDPSVRKEQYFKCVIFGKL 79
            :..||:|.|:||||.|||:||||.||||||.. |..||:|||:|..:....|.:.:|...||.::
  Fly    70 VTDFYSNATVLITGGTGFVGKVLTEKLLRSFG-LRKIYMLIRSKDNMSVQERLKGFFNESIFNRM 133

  Fly    80 LEKNPGIVDKVRVVKGDLLEPDLGLSANDTNTLASNVEVVFHCAANVRFDQPLRPMVMMNVVGTL 144
            .|::|.::.||..::.|....||.:.:.|...|:|.|::||:..|:|:|::.|...:.:||:||.
  Fly   134 REESPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTK 198

  Fly   145 KVLRLAEKMSQLQALVHVSTSYCQCNESVLEERAYPAPQNPFSIIEMVETMDDEALAEITPKLLN 209
            |:|.|..:|..|::.||:||.||.||...::|:.|........|:::..|.|||.|.::...|:.
  Fly   199 KILDLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQIYRTFDDETLEKMRHCLIG 263

  Fly   210 GLPNTYAYSKALSEDLICRYNNKLPIIITRPSIVTAAIHEPLPGWIEGVNGPTGLMIGAARGVIR 274
            .:||||..:|..:|:|:......:|..|.||.||.:...:|.|||.:.:.||:||...:|||::|
  Fly   264 QMPNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLVR 328

  Fly   275 SMHCNPDYASTVIPVDKAINGMILCGY---QRGKASQEKGNKQTGVEFCNLCISSKALMSWGDSI 336
            .::......:.::|.|..:|.||...:   :|.|..:.|.:.::.:...|. :|....::||..:
  Fly   329 CIYGKASCKANMVPADYVVNAMIATAWDIARRFKLRESKVDGKSELPVYNY-VSDANNITWGQYM 392

  Fly   337 ETGRRFFYETPLSFALWYPGGSIKKNYYHHLFCVIFFHYLPAYFIDFWLLVFGQKPFLLNVQRKV 401
            ...|:.|:| |...|||.....|..:...|.....|.|.:|||.:|...:|.|||........|:
  Fly   393 HLSRKGFHE-PFDKALWCFSYVIIPSKPLHCAIAFFLHNIPAYILDLIAMVTGQKRIYAKAYGKI 456

  Fly   402 SMGLKLLQYYTTKRWEFRNERFQEMSSQLSLLDQDLFDTSVGQVNWETYISNYIVGMRTYILGES 466
            |..:.::.::..|.|:|.:....|::..|...::.:...::..:||..|..:|:.|:|.|...:|
  Fly   457 SRIIDMMAWFGLKEWKFAHRNIDELNELLPREERSVLQFNIATINWSEYFRSYLSGIRRYFFKDS 521

  Fly   467 --EDTLPQARKVLRRLYILDWVSKVLF-FSLSFWFLWTHL 503
              ::.|.|.|.:.||:.||..:.|..| .||....|..:|
  Fly   522 ANDNKLQQRRTIYRRMLILHTLLKTTFGLSLIMCMLRVYL 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12268	NP_001247272.1	PLN02996	12..463	CDD:215538	145/450 (32%)
		FAR-N_SDR_e	22..347	CDD:187547	112/327 (34%)
		FAR_C	372..463	CDD:176924	24/90 (27%)
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	145/451 (32%)
		FAR-N_SDR_e	78..397	CDD:187547	109/320 (34%)
		Sterile	429..519	CDD:281068	23/89 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466767
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	9.000