DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12268 and Far2

DIOPT Version :9

Sequence 1:	NP_001247272.1	Gene:	CG12268 / 42833	FlyBaseID:	FBgn0039131	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	XP_006237759.1	Gene:	Far2 / 500368	RGDID:	1565966	Length:	515	Species:	Rattus norvegicus

Alignment Length:	527	Identity:	186/527 - (35%)
Similarity:	285/527 - (54%)	Gaps:	33/527 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SDIAKFYANKTILITGATGFMGKVLVEKLLRSCADLNVIYLLIRTKKGVDPSVRKEQYFKCVIFG 77
            |.||.||:||:|||||||||:||||:|||.|:...|.|||:|:|.|.|.....|..|.....:|.
  Rat     2 SMIAAFYSNKSILITGATGFLGKVLMEKLFRTSPHLKVIYILVRPKSGQTLQERVFQILNSKLFE 66

  Fly    78 KLLEKNPGIVDKVRVVKGDLLEPDLGLSANDTNTLASNVEVVFHCAANVRFDQPLRPMVMMNVVG 142
            ::.|..|.:.:|:|.:..||.:.|..:|..|...|.|...:||||||.||||..||..|.:||..
  Rat    67 RVKEVCPNVHEKIRPISADLNQRDFAISKEDMQELLSCTNIVFHCAATVRFDAHLREAVQLNVTA 131

  Fly   143 TLKVLRLAEKMSQLQALVHVSTSYCQCNESVLEERAYPAPQNPFSIIEMVETMDDEALAEITPKL 207
            |.::|.:|.:|.:|:|.:|:||::..||.|.::|..||.|..|..||:.:|.:||..:.||||||
  Rat   132 TQQLLLMASEMPKLEAFIHISTAFSNCNLSHIDEVIYPCPVEPRKIIDSMEWLDDSIIEEITPKL 196

  Fly   208 LNGLPNTYAYSKALSEDLICRYNNKLPIIITRPSIVTAAIHEPLPGWIEGVNGPTGLMIGAARGV 272
            :...||||.|:|||.|.::.:.:..|.:.|.|||||.|...||.|||::.:|||:||:|...:|.
  Rat   197 IGDRPNTYTYTKALGEVVVQQESGNLNVAIVRPSIVGATWQEPFPGWVDNLNGPSGLIIATGKGF 261

  Fly   273 IRSMHCNPDYASTVIPVDKAINGMILCGY----QRGKASQEKGNKQTGVEFCNLCISSKALMSWG 333
            :||:...|...:.:||||..:|..|..|:    .|.|::....:....:..||          |
  Rat   262 LRSIKATPMAVADLIPVDTVVNLTIAVGWYTAVHRPKSTLIYHSTSGNLNPCN----------W- 315

  Fly   334 DSIETGRRFF---YETPLSFALWYPGGSIKKNYYHHLFCVIFFHYLPAYFIDFWLLVFGQKPFLL 395
              .|.|.:..   .:.|...|...|......|.:...:.....|:.||...||:|.:.|:||.:|
  Rat   316 --YEMGLQVLATVEKIPFESAFRRPNADFTTNNFTTQYWNTVSHWAPAIIYDFYLRLTGRKPRML 378

  Fly   396 NVQRKVSMGLKLLQYYTTKRWEFRNERFQEMSSQLSLLDQDLFDTSVGQVNWETYISNYIVGMRT 460
            .:..::...:.:|:|:....||:.....:.:.|:||..||.:|:..|.|:||..||.||::|::.
  Rat   379 KLMNRLLKTISMLEYFINHSWEWSTNNTEMLLSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKK 443

  Fly   461 YILGESEDTLPQARKVLRRLYILDWVSKVLFFSLSFWFL-----------WTHLDGFVERSDAFI 514
            |:|.|....:|:|::.|:||..:.::.....| |..|.|           |..:..|..:..::.
  Rat   444 YLLKEDLAGIPKAKQHLKRLRNIHYLFNTALF-LIIWRLLIARSQMARNIWFFIVSFCYKFISYF 507

  Fly   515 RSSLSTI 521
            |:| ||:
  Rat   508 RAS-STL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12268	NP_001247272.1	PLN02996	12..463	CDD:215538	169/456 (37%)
		FAR-N_SDR_e	22..347	CDD:187547	129/331 (39%)
		FAR_C	372..463	CDD:176924	30/90 (33%)
Far2	XP_006237759.1	FAR-N_SDR_e	11..318	CDD:187547	127/319 (40%)
Far2	XP_006237759.1	Sterile	357..447	CDD:397244	30/89 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750