DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gdh and GDH2

DIOPT Version :9

Sequence 1:	NP_524470.4	Gene:	Gdh / 42832	FlyBaseID:	FBgn0001098	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001119183.1	Gene:	GDH2 / 830635	AraportID:	AT5G07440	Length:	411	Species:	Arabidopsis thaliana

Alignment Length:	356	Identity:	148/356 - (41%)
Similarity:	205/356 - (57%)	Gaps:	24/356 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 LMQPCDHI-IEIAFPLRRDAGNYEMITGYRAQHSTHKTPTKGGIRFSLDVSRDEVKALSALMTFK 162
            ||.|...| :|...|  :|.|......|:|.||...:.|.|||||:..:|..|||.||:.|||:|
plant    28 LMIPFREIKVECTIP--KDDGTLVSYIGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWK 90

  Fly   163 CACVDVPFGGAKAGLKINPKEYSEHELEKITRRFTLELAKKGFIGPGVDVPAPDMGTGEREMSWI 227
            .|..|:|:||||.|:..:|::.|..|||::||.||.::  ...||...|||||||||..:.|:||
plant    91 TAVADIPYGGAKGGIGCSPRDLSLSELERLTRVFTQKI--HDLIGIHTDVPAPDMGTNAQTMAWI 153

  Fly   228 ADTYAKTIGHLDINAHACVTGKPINQGGIHGRVSATGRGVFHGLENFINEANYMSQIGTTPGWGG 292
            .|.|:|..||    :.|.||||||:.||..||.:||||||....|..:.|.....|        |
plant   154 LDEYSKFHGH----SPAVVTGKPIDLGGSLGREAATGRGVVFATEALLAEYGKSIQ--------G 206

  Fly   293 KTFIVQGFGNVGLHTTRYLTRAGATCIGVIEHDGTLYNPEGIDPKLLEDYKNEHGTIVGYQNAKP 357
            .||::|||||||....:.:...|...:.|.:..|.:.||||||...|..:|:..|::..:.....
plant   207 LTFVIQGFGNVGTWAAKLIHEKGGKVVAVSDITGAIRNPEGIDINALIKHKDATGSLNDFNGGDA 271

  Fly   358 YEGENLMFEKCDIFIPAAVEKVITSENANRIQAKIIAEAANGPTTPAADKILIDRNILVIPDLYI 422
            ...:.|:..:||:.||.|:..|:..|||..::||.|.||||.||.|.||:||..:.::::||:|.
plant   272 MNSDELLIHECDVLIPCALGGVLNKENAGDVKAKFIVEAANHPTDPDADEILSKKGVIILPDIYA 336

  Fly   423 NAGGVTVSFFEWLKNLNHVSYGRLTFKYERE 453
            ||||||||:|||::|:.       .|.:|.|
plant   337 NAGGVTVSYFEWVQNIQ-------GFMWEEE 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gdh	NP_524470.4	GdhA	98..560	CDD:223411	148/356 (42%)
		ELFV_dehydrog_N	104..233	CDD:280903	58/129 (45%)
		NAD_bind_1_Glu_DH	254..552	CDD:133445	77/200 (39%)
GDH2	NP_001119183.1	PLN02477	1..410	CDD:178095	148/356 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1308
eggNOG	1	0.900	-	-		E1_COG0334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55885
Inparanoid	1	1.050	281	1.000	Inparanoid score	I872
OMA	1	1.010	-	-		QHG54967
OrthoDB	1	1.010	-	-		D692851at2759
OrthoFinder	1	1.000	-	-		FOG0001473
OrthoInspector	1	1.000	-	-		mtm1157
orthoMCL	1	0.900	-	-		OOG6_100455
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1737
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740