Protein Alignment Gdh and glud1

DIOPT Version :9

• Sequence 1: NP_524470.4
• Gene: Gdh / 42832
• FlyBaseID: FBgn0001098
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001011138.1
• Gene: glud1 / 496554
• XenbaseID: XB-GENE-1009691
• Length: 540
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 360/509 - (70%)
• Similarity: 430/509 - (84%)
• Gaps: 14/509 - (2%)

  Fly    54 DPRFFDMVEYFFHRGCQIAEESLVDDMKGKLTRDEKKQKVKGILMLMQPCDHIIEIAFPLRRDAG 118
            ||.||.|||.||.||..|.|:.||:|::.:.|.::|:.:|:|||.:::||:|::.::||::||.|
 Frog    45 DPNFFKMVEGFFDRGAGIVEDKLVEDLRTRETEEQKRLRVRGILRIIKPCNHVLSVSFPIKRDNG 109

  Fly   119 NYEMITGYRAQHSTHKTPTKGGIRFSLDVSRDEVKALSALMTFKCACVDVPFGGAKAGLKINPKE 183
            .:|:|.|||||||.|:||.|||||:|.:||.||||||::|||:|||.|||||||||||:|||.:.
 Frog   110 EWEVIEGYRAQHSQHRTPCKGGIRYSTEVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINTRN 174

  Fly   184 YSEHELEKITRRFTLELAKKGFIGPGVDVPAPDMGTGEREMSWIADTYAKTIGHLDINAHACVTG 248
            ||:.||||||||||:|||||||||||:|||||||.||||||||||||||.|||:.||||||||||
 Frog   175 YSDAELEKITRRFTIELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYANTIGYTDINAHACVTG 239

  Fly   249 KPINQGGIHGRVSATGRGVFHGLENFINEANYMSQIGTTPGWGGKTFIVQGFGNVGLHTTRYLTR 313
            |||:|||||||:||||||||||:|||||||:||||:|.|||:|.|||::|||||||||:.|||.|
 Frog   240 KPISQGGIHGRISATGRGVFHGIENFINEASYMSQLGMTPGFGDKTFVIQGFGNVGLHSMRYLHR 304

  Fly   314 AGATCIGVIEHDGTLYNPEGIDPKLLEDYKNEHGTIVGYQNAKPYEGENLMFEKCDIFIPAAVEK 378
            .||.|:|:.|.|||::||.|||||.|||||.:||||||:..|:||:| |::...|||.||||.||
 Frog   305 FGAKCVGIGEIDGTIWNPNGIDPKELEDYKLQHGTIVGFPKAQPYDG-NILEADCDILIPAASEK 368

  Fly   379 VITSENANRIQAKIIAEAANGPTTPAADKILIDRNILVIPDLYINAGGVTVSFFEWLKNLNHVSY 443
            .:|..||::|:||||||.|||||||.||||.::|||:||||||:||||||||:||||||||||||
 Frog   369 QLTKSNAHKIKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSY 433

  Fly   444 GRLTFKYERESNYHLLASVQQSIERIINDESVQESLERRFGRVGGRIPVTPSESFQKRISGASEK 508
            |||||||||:||||||.             ||||||||:||:.||.|||.|:..||.||||||||
 Frog   434 GRLTFKYERDSNYHLLM-------------SVQESLERKFGKHGGSIPVVPTAEFQARISGASEK 485

  Fly   509 DIVHSGLDYTMERSARAIMKTAMKYNLGLDLRTAAYVNSIEKIFTTYRDAGLAF 562
            |||||||.||||||||.||:||||||||||||||||||:|||:|..|.:|||.|
 Frog   486 DIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGLTF 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdh	NP_524470.4	GdhA	98..560	CDD:223411	335/461 (73%)
		ELFV_dehydrog_N	104..233	CDD:280903	95/128 (74%)
		NAD_bind_1_Glu_DH	254..552	CDD:133445	217/297 (73%)
glud1	NP_001011138.1	GdhA	86..528	CDD:223411	334/455 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1420
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55885
Inparanoid	1	1.050	752	1.000	Inparanoid score	I560
OMA	1	1.010	-	-		QHG54967
OrthoDB	1	1.010	-	-		D217293at33208
OrthoFinder	1	1.000	-	-		FOG0001473
OrthoInspector	1	1.000	-	-		oto104463
Panther	1	1.100	-	-	LDO	PTHR11606
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1737
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080