Protein Alignment Gdh and gdh-1

DIOPT Version :10

• Sequence 1: NP_524470.4
• Gene: Gdh / 42832
• FlyBaseID: FBgn0001098
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_502267.1
• Gene: gdh-1 / 178130
• WormBaseID: WBGene00014095
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 330/550 - (60%)
• Similarity: 417/550 - (75%)
• Gaps: 21/550 - (3%)

  Fly    18 LATLAK-ALPTAVMQSSRGYATEH-QIPDRLKDVPTAKDPRFFDMVEYFFHRGCQIAEESLVDDM 80
            |:||:: |...||...|......| |:.|..|.:....:|.|:.||:::|::|.::....|.:::
 Worm     2 LSTLSRGARSVAVRSYSAATLDAHSQVLDEQKPMEEQVNPSFYKMVDFYFNKGAEVIAPKLAEEL 66

  Fly    81 K-GKLTRDEKKQKVKGILMLMQPCDHIIEIAFPLRRDAGNYEMITGYRAQHSTHKTPTKGGIRFS 144
            | ..|::.:||..|.|||..::|.:.::.|.||:|||.|.:|:|..:|||||.|:||||||||:|
 Worm    67 KSNSLSQKDKKNLVSGILGAIKPVNKVLYITFPIRRDNGEFEVIEAWRAQHSEHRTPTKGGIRYS 131

  Fly   145 LDVSRDEVKALSALMTFKCACVDVPFGGAKAGLKINPKEYSEHELEKITRRFTLELAKKGFIGPG 209
            |||..|||||||||||:|||.|||||||||.|:||:||:|:::|:||||||..:|.|||||:|||
 Worm   132 LDVCEDEVKALSALMTYKCAVVDVPFGGAKGGVKIDPKQYTDYEIEKITRRIAIEFAKKGFLGPG 196

  Fly   210 VDVPAPDMGTGEREMSWIADTYAKTIGHLDINAHACVTGKPINQGGIHGRVSATGRGVFHGLENF 274
            |||||||||||||||.|||||||:||||||.:|.||:|||||..||||||||||||||:.|||.|
 Worm   197 VDVPAPDMGTGEREMGWIADTYAQTIGHLDRDASACITGKPIVSGGIHGRVSATGRGVWKGLEVF 261

  Fly   275 INEANYMSQIGTTPGWGGKTFIVQGFGNVGLHTTRYLTRAGATCIGVIEHDGTLYNPEGIDPKLL 339
            .|:|:||..:|...|..|||.|:||||||||||.|||.|||:..||:.|:|..:|||:||.||.|
 Worm   262 TNDADYMKMVGLDTGLAGKTAIIQGFGNVGLHTHRYLHRAGSKVIGIQEYDCAVYNPDGIHPKEL 326

  Fly   340 EDYKNEHGTIVGYQNAKPYEG-ENLMFEKCDIFIPAAVEKVITSENANRIQAKIIAEAANGPTTP 403
            ||:|:.:|||..:..||.::. ..||:||||||:|||.||.|..|||:|||||||||||||||||
 Worm   327 EDWKDANGTIKNFPGAKNFDPFTELMYEKCDIFVPAACEKSIHKENASRIQAKIIAEAANGPTTP 391

  Fly   404 AADKILIDR-NILVIPDLYINAGGVTVSFFEWLKNLNHVSYGRLTFKYERESNYHLLASVQQSIE 467
            |||:||:.| :.|:|||:|:|:||||||:|||||||||||||||||||:.|:|..||||||:|:.
 Worm   392 AADRILLARGDCLIIPDMYVNSGGVTVSYFEWLKNLNHVSYGRLTFKYDEEANKMLLASVQESLS 456

  Fly   468 RIINDESVQESLERRFGRVGGRIPVTPSESFQKRISGASEKDIVHSGLDYTMERSARAIMKTAMK 532
            :                .||...||.|:.:|..:|:||||||||||||:|||:||..||::||.|
 Worm   457 K----------------AVGKDCPVEPNAAFAAKIAGASEKDIVHSGLEYTMQRSGEAIIRTAHK 505

  Fly   533 YNLGLDLRTAAYVNSIEKIFTTYRDAGLAF 562
            ||||||:|||||.|||||::.|||.||..|
 Worm   506 YNLGLDIRTAAYANSIEKVYNTYRTAGFTF 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gdh	NP_524470.4	GdhA	54..560	CDD:440103	317/508 (62%)
gdh-1	NP_502267.1	GdhA	41..532	CDD:440103	316/506 (62%)