Protein Alignment Rpt2 and YTA12

DIOPT Version :10

• Sequence 1: NP_524469.2
• Gene: Rpt2 / 42828
• FlyBaseID: FBgn0015282
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_013807.1
• Gene: YTA12 / 855114
• SGDID: S000004695
• Length: 825
• Species: Saccharomyces cerevisiae
• Alignment Length: 571
• Identity: 154/571 - (26%)
• Similarity: 230/571 - (40%)
• Gaps: 166/571 - (29%)

  Fly     4 NQSAQGGAGEKKDDKDKKKKYEPPIPT---------RVGKKKRRAKG-------PDAAMKLPQVT 52
            |:..:..:|.|.:|.::..|....|||         :|.|...:.|.       .:...|:.:
Yeast    40 NRLQENKSGNKNEDNNEDAKLNKEIPTDEEVEAIRKQVEKYIEQTKNNTIPANWKEQKRKIDE-- 102

  Fly    53 PHTRCRLKLLKLERIKDYLMMEDEFIRNQERLKPQDEKNEEERSKVDDLRGTPMSVGNLEEII-- 115
                      .:.|::| .:::.|..|.||..|.::|:|...::|.:..:......||....|
Yeast   103 ----------SIRRLED-AVLKQESNRIQEERKEKEEENGPSKAKSNRTKEQGYFEGNNSRNIPP 156

  Fly   116 -----------DDNHAIVSTSVG-------------------------------------SEHYV 132
                       :|....||.:|.                                     ::.||
Yeast   157 PPPPPPPKPPLNDPSNPVSKNVNLFQIGLTFFLLSFLLDLLNSLEEQSEITWQDFREKLLAKGYV 221

  Fly   133 SILSFVDKDQLEPGCSVLLN--------------------------HKVHAVVGVLSDDTDPMVT 171
            :.|..|:|..::    |:||                          ||:......|..|.|..:.
Yeast   222 AKLIVVNKSMVK----VMLNDNGKNQADNYGRNFYYFTIGSIDSFEHKLQKAQDELDIDKDFRIP 282

  Fly   172 VM------------------------------------------------KLEKAPQET-----Y 183
            |:                                                |.:|...||     :
Yeast   283 VLYVQEGNWAKAMFQILPTVLMIAGIIWLTRRSAQAAGGSRGGIFGLSRSKAKKFNTETDVKIKF 347

  Fly   184 ADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLR 248
            .|:.|.|...:||.|.|.. |..|..||:||.|.|:|.||.|||||||||||||.|.:....|..
Yeast   348 KDVAGCDEAKEEIMEFVSF-LKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATAGEAGVPFYF 411

  Fly   249 VVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSN-SGGEREIQRTMLELL 312
            |.|||.::.::|.|...||:||:.|.|:||||||||||||:|..|...| ||...|.:.|:.::|
Yeast   412 VSGSEFVEMFVGVGAARVRDLFKTARENAPSIVFIDEIDAIGKARQKGNFSGANDERENTLNQML 476

  Fly   313 NQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDV 377
            .::|||.....|.|:..|||.:.||.||:||||.||.|....|:.:.::.||.:|...:.||.::
Yeast   477 VEMDGFTPADHVVVLAGTNRPDILDKALLRPGRFDRHINIDKPELEGRKAIFAVHLHHLKLAGEI 541

  Fly   378 -NLSELIMA-KDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKESVL 426
             :|...:.| ....|||||..:|.||.|:|.|.....|....|:::.|.|:
Yeast   542 FDLKNRLAALTPGFSGADIANVCNEAALIAARSDEDAVKLNHFEQAIERVI 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_524469.2	PTZ00361	1..439	CDD:185575	154/571 (27%)
YTA12	NP_013807.1	FtsH_ext	<205..282	CDD:377663	13/80 (16%)
		FtsH_fam	290..784	CDD:273520	111/304 (37%)