DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt2 and RPT2

DIOPT Version :9

Sequence 1:	NP_001287493.1	Gene:	Rpt2 / 42828	FlyBaseID:	FBgn0015282	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_010277.1	Gene:	RPT2 / 851557	SGDID:	S000002165	Length:	437	Species:	Saccharomyces cerevisiae

Alignment Length:	439	Identity:	311/439 - (70%)
Similarity:	376/439 - (85%)	Gaps:	2/439 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGQNQSAQGGAGEKKDDKDKKKKYEPPIPTRVGKKKRRAKGPDAAMKLPQVTPHTRCRLKLLKLE 65
            |||..|: |...:||...::|.|||||:.::.|:|||:. ||..|.|||.:.|.|||:||||::|
Yeast     1 MGQGVSS-GQDKKKKKGSNQKPKYEPPVQSKFGRKKRKG-GPATAEKLPNIYPSTRCKLKLLRME 63

  Fly    66 RIKDYLMMEDEFIRNQERLKPQDEKNEEERSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEH 130
            ||||:|::|:||:.|.|.|||.::|.|||:.:::::||.|:|:|.|||||||:||||::....::
Yeast    64 RIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDY 128

  Fly   131 YVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQE 195
            ||||||||||:.|||||||||:||..::||||.||.||||:|||::|:|.|:|:|||||::||||
Yeast   129 YVSILSFVDKELLEPGCSVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQE 193

  Fly   196 IKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLG 260
            |||||||||||||.||||||||||||||||.||||||||||||||||||||||:|||||||||||
Yeast   194 IKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLG 258

  Fly   261 DGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVK 325
            |||:|.|::|:||.|:||||||||||||:||||||||||||||||||||||||||||||.|||||
Yeast   259 DGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVK 323

  Fly   326 VIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLS 390
            ||||||:||||||||||||||||||.|..||..||::|..||||:|.|:|||||..|:..|||||
Yeast   324 VIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLS 388

  Fly   391 GADIKAICTEAGLMALRERRMKVTNEDFKKSKESVLYRKKEGTPEGLYL 439
            ||||:|:||||||:|||||||:||.||||::||.|:..|.|...|||||
Yeast   389 GADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_001287493.1	PTZ00361	1..439	CDD:185575	309/437 (71%)
RPT2	NP_010277.1	PTZ00361	1..437	CDD:185575	309/437 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343112
Domainoid	1	1.000	238	1.000	Domainoid score	I379
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2095
Inparanoid	1	1.050	624	1.000	Inparanoid score	I121
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54128
OrthoFinder	1	1.000	-	-		FOG0002872
OrthoInspector	1	1.000	-	-		oto98928
orthoMCL	1	0.900	-	-		OOG6_101477
Panther	1	1.100	-	-	LDO	PTHR23073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R998
SonicParanoid	1	1.000	-	-		X2230
TreeFam	1	0.960	-	-
	15	14.790