Protein Alignment Rpt2 and Psmc5

DIOPT Version :10

• Sequence 1: NP_524469.2
• Gene: Rpt2 / 42828
• FlyBaseID: FBgn0015282
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_112411.1
• Gene: Psmc5 / 81827
• RGDID: 708376
• Length: 406
• Species: Rattus norvegicus
• Alignment Length: 379
• Identity: 178/379 - (46%)
• Similarity: 258/379 - (68%)
• Gaps: 8/379 - (2%)

  Fly    59 LKLLKLERIKDYLMMEDEFIRNQERLKPQ-DEKNEEERSKVDDL-----RGTPMSVGNLEEIIDD 117
            |:...|.:|::..::.::..:|..||:.| :|.|.:.|...::|     :|:  .||.:...:|.
  Rat    20 LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGS--YVGEVVRAMDK 82

  Fly   118 NHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLEKAPQET 182
            ...:|......:..|.:...:|.:.:.|.|.|.|.:..:.:..:|.:..||:|::|.:||.|..|
  Rat    83 KKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDST 147

  Fly   183 YADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFL 247
            |..|||||.||:||||.:|||:.|||.:|.:||..||||:|||||||||||||:|||:.|..||:
  Rat   148 YEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFI 212

  Fly   248 RVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELL 312
            ||.||||:||::|:|.::|||||.:|.||||||:|:||||::|:.|.:..|||:.|:||||||||
  Rat   213 RVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELL 277

  Fly   313 NQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDV 377
            ||||||::..::|||||||||:.||.||:||||||||||||.|:|:.:..|..||:.:|.|...:
  Rat   278 NQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGI 342

  Fly   378 NLSELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKESVLYRKKE 431
            ||.::.......|||::|.:|||||:.||||||:.||.|||:.:...|:.:..|
  Rat   343 NLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSE 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_524469.2	PTZ00361	1..439	CDD:185575	178/379 (47%)
Psmc5	NP_112411.1	PRK03992	24..400	CDD:179699	177/375 (47%)
		May mediate interaction with PRPF9. /evidence=ECO:0000250|UniProtKB:P62196	186..406		123/211 (58%)