DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt2 and katnal2

DIOPT Version :9

Sequence 1:	NP_001287493.1	Gene:	Rpt2 / 42828	FlyBaseID:	FBgn0015282	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001032491.1	Gene:	katnal2 / 641431	ZFINID:	ZDB-GENE-051113-156	Length:	485	Species:	Danio rerio

Alignment Length:	379	Identity:	105/379 - (27%)
Similarity:	183/379 - (48%)	Gaps:	45/379 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KKRRAKGPDAAMKLPQVTPHTRCRLKLLKLERIKDYLMMEDEFIRNQERLKPQDEKNEEERSKVD 99
            ||...:|....:|......||..|:..::....::.:...:..:..::..|..|   .:..:..|
Zfish    91 KKLAEQGESRRIKSCGKRSHTLPRINSIQRPSSRNTVKKSESKLTGRDFSKSSD---GDRLTSAD 152

  Fly   100 DL---------------RGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSV 149
            .|               .||.|...:...:|.|  |:...:..:.|..   .|.::::|....|.
Zfish   153 TLGFGLNVSPIIRNGAEEGTHMRKIDYRNLIQD--AVRGAANDTLHNA---DFTEQERLLKPVSA 212

  Fly   150 L--LNHKVHAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEE 212
            |  :|..:..:..|:|.|       :.|.. |...:.||.||:...:.:||:|..|:.:|:.:..
Zfish   213 LIGMNSDMKELAAVISRD-------IYLHN-PNVRWDDIIGLEAAKRLVKEAVVYPIKYPQLFTG 269

  Fly   213 MGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHA 277
            : :.|.||::||||||||||:||||||.:.:.||..:..|.::.|:.||..||||.||.:|..||
Zfish   270 I-LSPWKGLLLYGPPGTGKTMLAKAVATECNTTFFNISASSIVSKWRGDSEKLVRVLFELARYHA 333

  Fly   278 PSIVFIDEIDAVGTKRYDSNSGGEREIQRTM-LELLNQLDGFDSRGD-VKVIMATNRIETLDPAL 340
            ||.:|:||:::|.::| ....||:.|..|.| .|||.|:||.....| |.|:.|:|....||.|:
Zfish   334 PSTIFLDELESVMSQR-GVGQGGDHEGSRRMKTELLVQMDGLARSNDLVFVLAASNLPWELDHAM 397

  Fly   341 IRPGRIDRKIEFPLPDEKTKRRIFT------IHTSRMTLAEDVNLSELIMAKDD 388
            :|  |::::|...||....::.:.:      .:|..:.|..:::...|...:::
Zfish   398 LR--RLEKRILVSLPSAPARQAMISHWLPPVSNTGGVELRTELDYDSLAQVQEE 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_001287493.1	PTZ00361	1..439	CDD:185575	105/379 (28%)
katnal2	NP_001032491.1	LisH	25..55	CDD:128913
		P-loop_NTPase	242..>296	CDD:304359	27/54 (50%)
		AAA	273..410	CDD:214640	63/139 (45%)
		AAA	277..409	CDD:278434	60/134 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900