Protein Alignment Rpt2 and PSMC2

DIOPT Version :9

• Sequence 1: NP_001287493.1
• Gene: Rpt2 / 42828
• FlyBaseID: FBgn0015282
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_002794.1
• Gene: PSMC2 / 5701
• HGNCID: 9548
• Length: 433
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 180/459 - (39%)
• Similarity: 266/459 - (57%)
• Gaps: 71/459 - (15%)

  Fly    10 GAGEKKDDKDKKKKYEPPIPTRVGKKKRRA--KGPDAAMKLPQVTPHTRCRLKLLKLERIKDYLM 72
            ||.::|..:|:|.  :.||         ||  :|..|.:|....:.::|         :||   .
Human     6 GADQRKTKEDEKD--DKPI---------RALDEGDIALLKTYGQSTYSR---------QIK---Q 47

  Fly    73 MEDEFIRNQERLKPQDEKNEEERSKVDDLRG--------------------------TPMSVGNL 111
            :||:.   |:.||           |:::|.|                          .|:.|...
Human    48 VEDDI---QQLLK-----------KINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARC 98

  Fly   112 EEII----DDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTV 172
            .:||    :|...|::....::..|.:...|....:|.|..|.::...:.:...|....||.||:
Human    99 TKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTM 163

  Fly   173 MKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKA 237
            |::|:.|..||:|:||...||::::|.||.||.|||.:..:||:|||||:|:|||||||||.|:|
Human   164 MQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARA 228

  Fly   238 VANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGGER 302
            |||:|.|.|:||:||||:|||:|:|.::|||||.:|......::|.|||||:|..|:|..:||:.
Human   229 VANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDN 293

  Fly   303 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIH 367
            |:|||||||:|||||||.||::||:|||||.:||||||:||||:||||||.|||.:.:..||.||
Human   294 EVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIH 358

  Fly   368 TSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKESVL--YRKK 430
            ...|::..|:....|.....:.:||:|:::|||||:.|:|.||...|.:||.::...|:  |.|.
Human   359 ARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKF 423

  Fly   431 EGTP 434
            ..||
Human   424 SATP 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_001287493.1	PTZ00361	1..439	CDD:185575	180/459 (39%)
PSMC2	NP_002794.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		5/17 (29%)
		RPT1	23..430	CDD:224143	173/431 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298123at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920