DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt2 and Kat60

DIOPT Version :9

Sequence 1:	NP_001287493.1	Gene:	Rpt2 / 42828	FlyBaseID:	FBgn0015282	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	113/352 - (32%)
Similarity:	181/352 - (51%)	Gaps:	59/352 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 GTPMSVGNLEEIIDDNHAIVSTSVGS--------EHYVSILSFVDKDQLEPGCSVLLNHKVHAVV 159
            |..:|..|..|..||:    ||:.|:        |:.....:..::.:.:|.     ||....:|
  Fly   254 GRKLSTSNTNEARDDD----STAAGNNGGAAGDGENGDPQAAQEEERKFQPN-----NHIEAELV 309

  Fly   160 GVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPP-KGVIL 223
            .:|..|.        |:|.|:..::||..|....:.::|:|.||:..|:|::  ||:.| |||::
  Fly   310 DILERDI--------LQKDPKVRWSDIADLHDAKRLLEEAVVLPMLMPDYFK--GIRRPWKGVLM 364

  Fly   224 YGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDA 288
            .||||||||:||||||.:...||..|..:.|..||.|:..|:||.||.:|..:|||.:||||||:
  Fly   365 VGPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDS 429

  Fly   289 VGTKRYDSNSGGERE---IQRTMLELLNQLDGFDSRGD----VKVIMATNRIETLDPALIRPGRI 346
            :.::|     |.|.|   .:|...|||.|:||.....:    |.|:.|||....:|.||.|  |:
  Fly   430 LCSRR-----GSESEHEASRRVKSELLVQMDGVGGGEEQAKVVMVLAATNFPWDIDEALRR--RL 487

  Fly   347 DRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMALR---- 407
            :::|..|||.::.:..:..|:...:.:.:.|:|:.:.......|||||..:|.||.:|::|
  Fly   488 EKRIYIPLPSDEGREALLKINLREVKVDDSVDLTYVANELKGYSGADITNVCREASMMSMRRKIA 552

  Fly   408 -------------ERRMKVTNEDFKKS 421
                         |..:.|:|:||.::
  Fly   553 GLTPEQIRQLATEEVDLPVSNKDFNEA 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_001287493.1	PTZ00361	1..439	CDD:185575	113/352 (32%)
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	28/57 (49%)
		AAA	358..496	CDD:214640	63/144 (44%)
		AAA	362..495	CDD:278434	59/139 (42%)
		Vps4_C	<570..603	CDD:286426	4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900