DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpt2 and Atad2

DIOPT Version :9

Sequence 1:	NP_001287493.1	Gene:	Rpt2 / 42828	FlyBaseID:	FBgn0015282	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001128351.1	Gene:	Atad2 / 314993	RGDID:	1304849	Length:	1373	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	138/486 - (28%)
Similarity:	217/486 - (44%)	Gaps:	128/486 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GQNQSAQGGAGEKKD-------DKDKKKK-----------YEPPIPTRVGKKKRRAKGPDAAMKL 48
            |:.|....|..|:.|       ::|.:|:           |:.|:     :|.|..:.|:.....
  Rat   250 GEEQEDDDGEDEEDDEDEEEDGEEDNQKRYYLRQRKATVYYQAPL-----EKPRHQRKPNMFYSG 309

  Fly    49 PQVTPHTRCRLK--------LLKLERIKDYLMMEDEFIRNQERLKPQDEKNEEERS--------- 96
            |......|.||.        ..::.|.:..:...|.   .......:||..|..|.
  Rat   310 PASPARPRYRLSSSGPRSPYCKRMNRRRHAIHSSDS---TSSSSSSEDECFERRRKRNRNRAINR 371

  Fly    97 ------KVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKV 155
                  :.|::||                                  :.||:::.|.::.
  Rat   372 CLPLNFRKDEIRG----------------------------------IYKDRMKIGANLA----- 397

  Fly   156 HAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKG 220
                     |.||    |:|:.:.:  :..:|||.:.|..:||.|..||.:||.:|:..|:||:|
  Rat   398 ---------DVDP----MQLDSSVR--FDSVGGLSSHIAALKEMVLFPLLYPEVFEKFKIQPPRG 447

  Fly   221 VILYGPPGTGKTLLAKAVANQTS------ATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPS 279
            .:.||||||||||:|:|:||:.|      |.|:| .|::.:.|::|:..:.:|.||..|.:..|:
  Rat   448 CLFYGPPGTGKTLVARALANECSRGDKRVAFFMR-KGADCLSKWVGESERQLRLLFDQAYQMRPA 511

  Fly   280 IVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPG 344
            |:|.||||.:...|..........|..|:|.|   :||.||||::.||.||||::::||||.|||
  Rat   512 IIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL---MDGLDSRGEIVVIGATNRLDSIDPALRRPG 573

  Fly   345 RIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLS-------GADIKAICTEAG 402
            |.||:..|.|||:..::.|..|||      .|.|...:.|..::|:       |||||:||.||.
  Rat   574 RFDREFLFSLPDKDARKEILKIHT------RDWNPKPVDMFLEELAENCVGYCGADIKSICAEAA 632

  Fly   403 LMALRER--RMKVTNEDFKKSKESVLYRKKE 431
            |.|||.|  ::..|:|..:....|:....|:
  Rat   633 LCALRRRYPQIYTTSEKLQLDLSSINISAKD 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_001287493.1	PTZ00361	1..439	CDD:185575	138/486 (28%)
Atad2	NP_001128351.1	AAA	444..585	CDD:214640	64/144 (44%)
		AAA	449..583	CDD:278434	60/137 (44%)
		Bromo_AAA	972..1082	CDD:99957
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900