DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpt2 and CG10793

DIOPT Version :9

Sequence 1:	NP_001287493.1	Gene:	Rpt2 / 42828	FlyBaseID:	FBgn0015282	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_570054.2	Gene:	CG10793 / 31308	FlyBaseID:	FBgn0029656	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	407	Identity:	106/407 - (26%)
Similarity:	176/407 - (43%)	Gaps:	93/407 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KKYEPPIPTRVGKKKRRAKGPDAAMKLPQVTPHTRCRL-----------KLLKLERIKDYLMMED 75
            ||....|...:|..|...|.|  |.:||:..|.|...|           :.|..|:......||.
  Fly    93 KKVGAKIKVEMGGGKAHEKTP--AKELPKKPPTTDASLANWHIGVGAATQALSNEQPLQIKKMET 155

  Fly    76 EFIRNQERLKPQDEKNEEERSKV--DDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFV 138
            ....|     .||...|.|...:  ||:..:.:...:|.|       :|.||:..|
  Fly   156 ATESN-----GQDNACEIEHVHLGGDDVLFSSLEWQSLAE-------LVKTSILQE--------- 199

  Fly   139 DKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELP 203
                         |.|:                          .::|:.|....|:.|||:|..|
  Fly   200 -------------NIKI--------------------------KWSDVCGNQRAIELIKEAVLTP 225

  Fly   204 LTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT--SATFLRVVGSELIQKYLGDGPKLV 266
            :..|:.:.. |:||.:.::|:||||:||||||||:.::|  ..||..:..|.::.|:.|:..|::
  Fly   226 IEFPQLFAH-GLKPWRSLLLHGPPGSGKTLLAKALYSETQGQVTFFNITASIMVSKWRGESEKIL 289

  Fly   267 RELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFD-SRGDVKVIMAT 330
            |.||.:|.:.|||::|.|||:::.:||  ..:......:|...|||..|||.: |...|.|:.:|
  Fly   290 RVLFHMAAKRAPSVIFFDEIESLTSKR--DRATDHESSKRFKNELLQLLDGMEHSLNGVFVLAST 352

  Fly   331 NRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLS-----ELIMAKDDLS 390
            |....:|.|.:|  |.::|:...||:...:..:.    :|: |...::|:     :|:...|..:
  Fly   353 NLPWDIDEAFLR--RFEKKLLVQLPNAAERSCLI----NRL-LGSSISLNPRLLEQLVEISDHFT 410

  Fly   391 GADIKAICTEAGLMALR 407
            |.:|:..|.|..:..:|
  Fly   411 GDEIRLACKEISMHRVR 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_001287493.1	PTZ00361	1..439	CDD:185575	106/407 (26%)
CG10793	NP_570054.2	LisH	31..56	CDD:285685
		P-loop_NTPase	205..>259	CDD:304359	24/54 (44%)
		AAA	238..376	CDD:214640	52/141 (37%)
		AAA	242..374	CDD:278434	50/135 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900