Protein Alignment Rpt2 and ATAD2

DIOPT Version :9

• Sequence 1: NP_001287493.1
• Gene: Rpt2 / 42828
• FlyBaseID: FBgn0015282
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_054828.2
• Gene: ATAD2 / 29028
• HGNCID: 30123
• Length: 1390
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 143/512 - (27%)
• Similarity: 223/512 - (43%)
• Gaps: 155/512 - (30%)

  Fly     2 GQNQSAQGGA-------GEKKDDKD--------------------------------KKKK---- 23
            |..:|::.|.       ||.:||:|                                :::|
Human   240 GSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQKRYYLRQRKATVY 304

  Fly    24 YEPPIPTRVGKKKRRAKGPDAAMKLPQVTPHTRCRLK--------LLKLERIKDYLMMEDEFIRN 80
            |:.|:     :|.|..:.|:.....|......|.||.        ..::.|.:..:...|    :
Human   305 YQAPL-----EKPRHQRKPNIFYSGPASPARPRYRLSSAGPRSPYCKRMNRRRHAIHSSD----S 360

  Fly    81 QERLKPQDEKNEEERSK----------------VDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSE 129
            ......:||::.|.|.|                .|:|:|
Human   361 TSSSSSEDEQHFERRRKRSRNRAINRCLPLNFRKDELKG-------------------------- 399

  Fly   130 HYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQ 194
                    :.||:::.|.|:.              |.||    |:|:.:.:  :..:|||...|.
Human   400 --------IYKDRMKIGASLA--------------DVDP----MQLDSSVR--FDSVGGLSNHIA 436

  Fly   195 EIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTS------ATFLRVVGSE 253
            .:||.|..||.:||.:|:..|:||:|.:.||||||||||:|:|:||:.|      |.|:| .|::
Human   437 ALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMR-KGAD 500

  Fly   254 LIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGF 318
            .:.|::|:..:.:|.||..|.:..|||:|.||||.:...|..........|..|:|.|   :||.
Human   501 CLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL---MDGL 562

  Fly   319 DSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELI 383
            ||||::.||.||||::::||||.||||.||:..|.|||::.::.|..|||      .|.|...|.
Human   563 DSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHT------RDWNPKPLD 621

  Fly   384 MAKDDLS-------GADIKAICTEAGLMALRER--RMKVTNEDFKKSKESVLYRKKE 431
            ...::|:       |||||:||.||.|.|||.|  ::..|:|..:....|:....|:
Human   622 TFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKD 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt2	NP_001287493.1	PTZ00361	1..439	CDD:185575	143/512 (28%)
ATAD2	NP_054828.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..63
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..380		25/148 (17%)
		AAA	459..600	CDD:214640	65/144 (45%)
		AAA	464..598	CDD:278434	61/137 (45%)
		COG5076	<915..1153	CDD:227408
		Bromo_AAA	987..1097	CDD:99957
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1124..1163
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1181..1242

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900