Protein Alignment Ndc1 and ndc1

DIOPT Version :10

• Sequence 1: NP_651191.1
• Gene: Ndc1 / 42825
• FlyBaseID: FBgn0039125
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: NP_956237.1
• Gene: ndc1 / 335236
• ZFINID: ZDB-GENE-030131-7176
• Length: 671
• Species: Danio rerio
• Alignment Length: 672
• Identity: 143/672 - (21%)
• Similarity: 275/672 - (40%)
• Gaps: 127/672 - (18%)

  Fly    13 LLLGRCLRAVLLSVAIQFLLLTVFLLFVNFQLLHPLAWVTGTLRLVASWYTWFASIPLVASVVLY 77
            :::.|.:.::..||.:..:...||:|...|.|.||:.|::....|:.:..|.|:.:.|.|.|::.
Zfish    14 VVIWRAVASIAWSVLLLPITTAVFVLLSRFSLFHPIQWISDCTNLLTASSTIFSLMVLCAVVLIT 78

  Fly    78 GVILCQQHLSERRYCPTRYRWL---LHYGPRKVLFLFAHLLVGLLTAWLYTGYLHTDYQHLKYKC 139
            |....:.:........:|...|   ||  |.:.:....:..:|:|..|..:..:...|..|...|
Zfish    79 GFFNLEFYTLVPSIPCSRVALLGTVLH--PLQCVHSLVYSSMGMLVMWCASVIISGRYSTLGTPC 141

  Fly   140 YGQD------CISAYNVYLLGIGMTAG-CYYFVSVHMRKEISIEFPIVEQSRAEKMRELLYASLA 197
            ...:      |::.|:::||..|...| .:.|:.| ::....:.|..::|.:..:.:..|...|.
Zfish   142 MQNESGDVLTCLNEYHLFLLLAGAFMGYSHSFLGV-VKNMYYVSFQPIQQYKYPQFKGCLPMLLK 205

  Fly   198 KSLLSSLLPTISYTAVFCLFGPMVCHRLSHILSVDMD---ERLDGFFGVVTNVRLLFYGYLLTAQ 259
            .|::.||..|.::.|::..||.:....:|..|::.:|   :.||...|:: :..||::..:....
Zfish   206 CSVIQSLYSTRNFAALYFFFGYVPRAWISSTLNLPIDSSLQPLDSLTGLL-DFSLLYHLSISGTF 269

  Fly   260 ILSNMHLMRCFYGILLSEDLPLVVTKPRAAFAHEQDITLVAGLGVFNVYVVQCLAAHHFYKLALR 324
            :....:|....:.|..:|.....|   ::.|:.:.:..|...:|..:..|::.||....  ..|.
Zfish   270 LYFTWYLTVLIFRIYATEAYSFPV---QSTFSEDAERCLPKVVGEKSTLVMKFLALQDL--ALLS 329

  Fly   325 KNSP-QRAEIFQLTEPGNRPASWRSLCDQCLSILGSFTEELTESMQKI----------------- 371
            ::|| :|.|:|.|::||..|.:|.::..:||.:|...|:.|......:
Zfish   330 QHSPSRRQEVFSLSQPGGHPHNWNAISGECLCLLRDLTQRLVAHQDAVASNGRVKSQSASSDTRS 394

  Fly   372 -----SILKCAQSLP-MPKITESLTT--------------------------------------- 391
                 |:|...:.:| .|:.|..|.|
Zfish   395 ASSSSSVLSGMEDVPETPRPTVPLRTPGSVFKSSVGGMHSSLTAPFTPDVDSPFCSPAIRRLVGQ 459

  Fly   392 ---------SLMAEKVLLR-----------QYNQKHGIRPIVSPSREVAVESPADGIRHFPNWCE 436
                     ::.:..::.|           |.|......|.::||...|.:.|:    ....|.:
Zfish   460 QDPQSPWFGTVQSPHIMRRGPKLWSASTESQSNGSPPASPAIAPSPPAANKKPS----FLAQWLQ 520

  Fly   437 RVSTQLEQSL-QRLLQRVPGIVYLFNEPEGAKTTFLLANSLPVVYMTQALAQVCAASLKEDPYGV 500
            ....|::..| :|:|     ||||||:...|.:..|.|:|...::..|.|:.:.|||..||.:||
Zfish   521 NRKEQVKSFLAKRVL-----IVYLFNKLPEASSQALFADSQAHIWALQGLSHLVAASFSEDQFGV 580

  Fly   501 VQNDLPAIIKAINKLRNELD---KLSSVIGN-----IRISSSSFNVLRCAVRRSL----YAICLS 553
            ||..||:|:.::..|...:|   ||......     ..:..|::..||.|:|.:|    |.|..:
Zfish   581 VQTTLPSILSSLVVLLEAVDRHFKLPHASSKPARTVCSMGDSTYKTLRFALRAALKTAIYKITTT 645

  Fly   554 FCDYLDDLLPPGEELRQLQDLV 575
            |.::|:.:....|..::||..:
Zfish   646 FGEHLNAVNISTEHRKRLQQFL 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndc1	NP_651191.1	Ndc1_Nup	63..572	CDD:462824	129/617 (21%)
ndc1	NP_956237.1	Ndc1_Nup	13..664	CDD:462824	141/667 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..420		6/41 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	480..508		5/27 (19%)