Protein Alignment sba and Mbd6

DIOPT Version :9

• Sequence 1: NP_001262888.1
• Gene: sba / 42824
• FlyBaseID: FBgn0016754
• Length: 1606
• Species: Drosophila melanogaster
• Sequence 2: XP_006241525.1
• Gene: Mbd6 / 362892
• RGDID: 1311050
• Length: 1006
• Species: Rattus norvegicus
• Alignment Length: 1262
• Identity: 267/1262 - (21%)
• Similarity: 381/1262 - (30%)
• Gaps: 435/1262 - (34%)

  Fly   233 NGNINRKTATSYNGNLAP-----GWRRLTNNNEVAYISPSGKTLRTQFQIKDYLLTQGTCKCGLP 292
            ||. |..:|....|..|.     ||:|......|.||||||..|.:..|.:.|||:.|||||||.
  Rat     2 NGG-NESSAADRAGGPAATAVPIGWQRCVREGAVYYISPSGTELSSLEQTRSYLLSDGTCKCGLE 65

  Fly   293 CPLRPEYLFDFNAQVPNQPLKL---PTEASTATPTPCRHQRRFLESQQLQLPQQQQQQQHLQHQQ 354
            |||....:|:|:...|..|...   |......|.. |.|:|:.:....|    .:..:....|..
  Rat    66 CPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKL-CNHRRKAVAMATL----YRSMETTCSHSS 125

  Fly   355 QQQQAVKDVSVDVAVSVS-GPAAVSDVFSTLMTSTARTATMVTPTAATSPAQAATTTTH------ 412
            ..:.|    |..:..:|| |||:|........|:.........|....|..||....|.
  Rat   126 PGEGA----SPQMFHTVSPGPASVRPSCRVPPTTPLNGGPGSIPQEPPSVPQAFPPLTGPAGLFP 186

  Fly   413 -------EMANKDADCHKYGNNKLPATNRTATTPTPAPTPP-------PQHPNGMPTSQALA--- 460
                   ..|...:.|.      ||..|    .|:|||.||       |.:..|......|.
  Rat   187 PRLPDPVPSAGSSSPCF------LPRGN----APSPAPPPPSAISLNAPSYNWGASLRSNLVPSD 241

  Fly   461 LGGVPVGVHPKRPTGGHVIKQPASVLGPPCTPPLAVGGANTVIQQQQPLQQHPNFKDDPAGYLQQ 525
            ||..|.......|.....:...:..|.||..||     :|.:          |.....|....|.
  Rat   242 LGSPPAPHASSSPPSDSPLFHCSDALTPPPVPP-----SNNL----------PGPPGPPGSTTQP 291

  Fly   526 --QTALLHNSLGVGLDATKTAAGTSTARALPQEPIVHSSQQQQQQQQQQLQQQQQLQRQKIRRLS 588
              .:|.:|..|.:|     :..|..|.......|.:.||.
  Rat   292 PVSSATMHLPLVLG-----SLGGGPTVEGPGAPPFLASSL------------------------- 326

  Fly   589 LFGKWETDPAPATNSQPTNGTRALQVDAAAFARPQKPQVTCVTLVPPPQESPVSSSAAETLEKRP 653
                                       .:|.|:.|:||      :|||          .||:.|.
  Rat   327 ---------------------------LSAAAKAQQPQ------LPPP----------STLQGRR 348

  Fly   654 EQVGAISTSHESPRQSL------------------SSPTDSVDSAKS-TPSASPKPQTQVPMQPQ 699
            .:..|.|.||.|||.|.                  .||..|...|.: .|...|.|:...|:.|.
  Rat   349 PRAQAPSASHASPRPSQRRPRRPPTVLRLLEGGGPQSPRRSRPRAPAPVPQPFPLPEPSQPILPS 413

  Fly   700 LLQMRPHLQANLSAQTPVTVPAHVR---VMRQQQAQIIPGQRLPVASSSAAMATMTRSIVTSTAG 761
            :|.:       |...||  .|:|..   .:....|.:.|    |.|.||.:.......|..|..|
  Rat   414 VLSL-------LGLPTP--GPSHSDGSFNLLGSDAHLPP----PPALSSGSPPQPRHPIQPSLPG 465

  Fly   762 T-----STITGRPVATTLNNSNPTVAQ--LQSMANAMNGAGGG---------GQ----------- 799
            |     |::.|.|.....:.: |.|..  |||..:...|.|.|         |:
  Rat   466 TTSGSLSSVPGAPAPPAASKA-PVVPSPVLQSPCDKGLGLGAGPACPLPPLAGEEAFPFPSPEQG 529

  Fly   800 LIMTSS---GQLLVIPTPSKQTTQHHRPGQPGQGVIIQ-----------QQQPAELHPQPGG--- 847
            |.::.:   |.|..:|.|...       |||....::.           |..|..|.|.|||
  Rat   530 LALSGAGFPGMLGALPLPLSL-------GQPPPSPLLSHSLFGVLAGAGQPPPEPLLPPPGGPGP 587

  Fly   848 --------------GYIVSQP-----SPVAAASSSSSSSTVILNSGGAKLLHHQIITSQAGQINQ 893
                          ..::|.|     .|.|..|:..:|...:|..|.         |:..|:.:.
  Rat   588 PLAPGEPEGPSLLVASLLSPPPSDLLPPPAPPSNLLASFLPLLALGP---------TAGDGEGSA 643

  Fly   894 ATSGGSGNQPQTVLLNTLP---------------NGGYIVQQ-QPQTQSPQQAEQILAMPQP-PP 941
            ..:||...:|.:.|.:..|               |...:... .|.:.:|.| ..:|:.||| ||
  Rat   644 EGAGGPNGEPFSGLGDLPPLLFPPLSAPPTLIALNSALLAASLDPPSGTPPQ-PCVLSAPQPGPP 707

  Fly   942 AQTLIISSPDTKRRARKRKSSVCHTPPPSGSPAKIISPQISPSIPNQAPALLHQQAAAAAAAAPQ 1006
            ..::..::.|      ...||:...|..||.|.:::||.:|.|:.....:|..
  Rat   708 TSSVTTATTD------PGASSLGKAPSNSGRPPQLLSPLLSASLLGDLSSLTS------------ 754

  Fly  1007 FQQQFQLSPGIQGIVVNKPNPPQQPQTQQLLLQNGQILQQVNLIGQQLLMPAGL------VMGPD 1065
                   |||....::..|.|....|                 :|.|||...|.      ...|.
  Rat   755 -------SPGTLPSLLQPPGPLLSSQ-----------------LGLQLLPGGGAPPTLSEASSPL 795

  Fly  1066 ATLLQ-IQNMPA----TSLMTPQGPVMLRTPSPQNKP-SFISPSAG------------------- 1105
            |.||| :|.:|.    ...:.|:.|.....|.|...| |.::|..|
  Rat   796 ACLLQSLQQIPPEQPDAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRG 860

  Fly  1106 --GQQYLVGANGQLSPIGQ-----IYSTPMGLVMPTGQQGGASFVQASPTTTTIQIQQQPAPQPT 1163
              |...|.|.||:..| |:     ....|..|.:..|.:||.:                     .
  Rat   861 RRGGGGLRGINGETRP-GRGRKPGSRREPGRLALKWGTRGGFN---------------------G 903

  Fly  1164 QISLQPAQATYMTETVMSRQGTAASPPDTTTCSPRSPERPSSHRSSGSDMVQCVSSSEPDAAVSP 1228
            |:...|.:..:........:|.|         .|:.|..|..|              ..|..|||
  Rat   904 QMERSPRRTHHWQHNGELAEGGA---------EPKDPPLPGPH--------------PEDLKVSP 945

  Fly  1229 QSTESRQSPSSTDCERSICKNNVFTQPSGIYKHSEPKIRRIHITSQTSAENGISLMQGQESPTTT 1293
                                        ||.:.|....||.:..::.|:.:....:..:.||||.
  Rat   946 ----------------------------GIVRKSRRGRRRKYNPARNSSSSSRQDVTLEPSPTTR 982

  Fly  1294 QLLSSVPTAQPTVEKTTVRTPTKRSRR 1320
            ..:...|.|:|       ..|.|..||
  Rat   983 AAVPLPPRARP-------GRPAKNKRR 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sba	NP_001262888.1	MBD	241..315	CDD:128673	32/81 (40%)
		PWWP	1344..1440	CDD:295359
Mbd6	XP_006241525.1	MBD	21..84	CDD:412167	28/62 (45%)
		PHA03247	<140..566	CDD:223021	110/544 (20%)
		PHA03247	<394..890	CDD:223021	119/569 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354536
Domainoid	1	1.000	84	1.000	Domainoid score	I8133
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46429
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16112
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.030