DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-1 and cecr2

DIOPT Version :9

Sequence 1:	NP_001369030.1	Gene:	tbrd-1 / 42823	FlyBaseID:	FBgn0039124	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	XP_005174419.1	Gene:	cecr2 / 799918	ZFINID:	ZDB-GENE-131121-533	Length:	1502	Species:	Danio rerio

Alignment Length:	354	Identity:	91/354 - (25%)
Similarity:	122/354 - (34%)	Gaps:	99/354 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IPP---------PNRPGRRTNILEE-------LKSVLNCLWRNRFSYHFRHPVDSVSLGVPDYHA 79
            :||         |.|..|||....|       |..||..|..::.::.|..|||...  .|:||.
Zfish   376 LPPELLNLETHSPIRRARRTKQFYEIDDDYTALYKVLEALKAHKDAWPFMEPVDESY--APNYHE 438

  Fly    80 VVKHPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLMEAF----YMR 140
            :::.|||||||.::|::..|....|.:.|.||:|.|||.||.|.|......:.|...|    ...
Zfish   439 IIQTPMDLSTIERKLNDGEYLAKDEFVADVKLMFGNCLEYNGEESEYTIMAESLERCFTRALLKH 503

  Fly   141 MESIDLSTEVELKPKSEKRKRK----------------ATESLDQASTSFSAPRASNNYSRQWLS 189
            ..|.|..|:.|....||.||.|                |||.:.:..||.|.  ..||..::
Zfish   504 FPSEDGDTDEEFHVSSEDRKDKKKNKNHKQSGPESLIRATEQVQKRKTSNSG--KGNNQQQE--- 563

  Fly   190 SSSSWLCPPPMPGGVSSFNPSFRNFVGPSLIPSFMPDSLVNPMQSMHPMSSMMNPIFKNNWETNE 254
            ...|.|.|||         |.:.|  ||....:..|......|  :||......|.....:..:.
Zfish   564 KPKSTLQPPP---------PHYSN--GPPHPHNIHPGQQQRGM--LHPAQQFQRPSGPGMYAQHM 615

  Fly   255 AMDP----PPSEPISYRP-----------------------------LDSLAAPLPSPPMEPMTL 286
            .:|.    |...|:..||                             :.....|| .||.:..:.
Zfish   616 MIDAQYPYPGQRPLISRPPGDHENQHVPHFNMQGSHINGPHLGTRYTVGPDGQPL-QPPHQQHSY 679

  Fly   287 PWPTPAPVESP---------ASSPPPAPN 306
            ..||..|...|         ..||||..|
Zfish   680 SGPTHGPSLGPRPMALQPGGLCSPPPEGN 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_001369030.1	Bromodomain	39..143	CDD:413371	38/114 (33%)
tbrd-1	NP_001369030.1	Bromodomain	328..423	CDD:413371
cecr2	XP_005174419.1	DDT	23..63	CDD:280886
		ARGLU	202..366	CDD:291991
		Bromo_gcn5_like	403..503	CDD:99941	34/101 (34%)
		Med15	675..>1110	CDD:255446	9/34 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900