DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-1 and Brd8

DIOPT Version :9

Sequence 1:	NP_001369030.1	Gene:	tbrd-1 / 42823	FlyBaseID:	FBgn0039124	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001348065.1	Gene:	Brd8 / 78656	MGIID:	1925906	Length:	954	Species:	Mus musculus

Alignment Length:	160	Identity:	46/160 - (28%)
Similarity:	73/160 - (45%)	Gaps:	26/160 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KSVLNCLWR----NRFSYHFRHPV-DSVSLGVPDYHAVVKHPMDLSTIRKRLHNKYYWQASEALE 107
            |..:..:||    :|::..|..|| |.::   |.||::|:.|||||||:|.:.|......:|...
Mouse   786 KKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQR 847

  Fly   108 DFKLIFDNCLLYNLEGSPVY------------QAGKLLMEAFYMRMESIDLSTEVELKPKSEKRK 160
            |..|:|.|.::||.....||            |..:.|.....|:.....:|.: .|:.:...||
Mouse   848 DIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAK-SLRGRDSTRK 911

  Fly   161 RKATE--SLDQASTSFSAPRASNNYSRQWL 188
            :.|:|  |:...|.:|   ..|...|.:||
Mouse   912 QDASEKDSVPMGSPAF---LLSLFVSIEWL 938

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_001369030.1	Bromodomain	39..143	CDD:413371	33/111 (30%)
tbrd-1	NP_001369030.1	Bromodomain	328..423	CDD:413371
Brd8	NP_001348065.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..273
		Atrophin-1	<176..356	CDD:331285
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	520..547
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	584..745
		Bromo_brd8_like	782..885	CDD:99939	31/101 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	900..922		6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900