Protein Alignment tbrd-1 and Pbrm1

DIOPT Version :9

• Sequence 1: NP_001369030.1
• Gene: tbrd-1 / 42823
• FlyBaseID: FBgn0039124
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001074720.1
• Gene: Pbrm1 / 66923
• MGIID: 1923998
• Length: 1704
• Species: Mus musculus
• Alignment Length: 605
• Identity: 121/605 - (20%)
• Similarity: 191/605 - (31%)
• Gaps: 216/605 - (35%)

  Fly     5 QSNSNQPPPRNEP-YLQPVNGIVQPPVIPPPNRPGRRTNILEELKSVLNCLWRNRFSYHFRHPVD 68
            |.|.......:.| ||:.:...:...::...|..||   ::.||...|    .::..|
Mouse   167 QDNQGTLADGSSPGYLKEILEQLLEAIVVATNPSGR---LISELFQKL----PSKVQY------- 217

  Fly    69 SVSLGVPDYHAVVKHPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLL 133
                  |||:|::|.|:||.||.:|:.|..|.......:|..|:..|...||..||.|::....:
Mouse   218 ------PDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSI 276

  Fly   134 MEAFYMRMESIDLSTEVELKPKSEKRKRKATESLDQASTSFSAPRASNNYSRQWLSSSSSWLCPP 198
            .:.|||:...|    |.....||..|.|.|:.......|..|..::|....|.  .:|..:....
Mouse   277 KKIFYMKKAEI----EHHEMTKSSLRIRTASNLAAARLTGPSHNKSSLGEERN--PTSKYYRNKR 335

  Fly   199 PMPGG-----------------------------------VSSF----NP---------SFRNFV 215
            .:.||                                   ::||    ||         |.||..
Mouse   336 AVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFHQLYDTVRSCRNHQ 400

  Fly   216 GPSLIPSF--MPDSLVNP---MQSMHPMS-SMMNPIFKNNWETNEAMDPPPSEPISYRPLDSLAA 274
            |..:...|  :|.....|   .|...|:| ..:....||.               .|..||.|..
Mouse   401 GQLIAEPFFHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQ---------------EYETLDHLEC 450

  Fly   275 PLPSPPMEPMTLPWPTPAPVESPASSPPPAPNPPIIICYKSL----------------------- 316
            .|        .|.:........|.|:           .||.:
Mouse   451 DL--------NLMFENAKRYNVPNSA-----------IYKRVLKLQQVMQAKKKELARRDDIEDG 496

  Fly   317 DRMIEKSHSDHLLKSMVKRKR---------------------KQVTWAFN--------------- 345
            |.||..:.||   ....||||                     :::...||
Mouse   497 DSMISSATSD---TGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLC 558

  Fly   346 --------QADYWRRYSQNPDYDHDREEKLDWKILQERLDSDNFESFDGFVSSVRKMFQNALRCF 402
                    :.||       |||.....|.:|.||::..:.:|.:...:|.:..::.||:|| |.:
Mouse   559 DLFMVKPSKKDY-------PDYYKIILEPMDLKIIEHNIRNDKYAGEEGMMEDMKLMFRNA-RHY 615

  Fly   403 PEDGLVKVSVKKTNEIFEKRLPKYRELIATAKEKGRQLVASREQDFRDSQNLLIKQENANKNFKG 467
            .|:|   ..|.....|.||.|          |:|.::|....:.|...|..|.:.:::      |
Mouse   616 NEEG---SQVYNDAHILEKLL----------KDKRKELGPLPDDDDMASPKLKLSRKS------G 661

  Fly   468 WVPKPFIIKTESLFVQEQRV 487
            ..||    |::.:...:|::
Mouse   662 VSPK----KSKYMTPMQQKL 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_001369030.1	Bromodomain	39..143	CDD:413371	29/103 (28%)
		Bromodomain	328..423	CDD:413371	28/138 (20%)
Pbrm1	NP_001074720.1	Bromo_polybromo_I	44..156	CDD:99954
		Bromo_polybromo_II	182..284	CDD:99948	32/121 (26%)
		Bromo_polybromo_III	383..484	CDD:99951	24/134 (18%)
		Bromo_polybromo_IV	534..637	CDD:99949	26/123 (21%)
		Bromo_polybromo_V	673..777	CDD:99946	1/5 (20%)
		Bromo_polybromo_VI	790..897	CDD:99956
		BAH_polybromo	972..1089	CDD:240068
		BAH_polybromo	1170..1288	CDD:240068
		HMG-box	1395..1459	CDD:238037

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900