DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-1 and nej

DIOPT Version :9

Sequence 1:	NP_001369030.1	Gene:	tbrd-1 / 42823	FlyBaseID:	FBgn0039124	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001188575.1	Gene:	nej / 43856	FlyBaseID:	FBgn0261617	Length:	3282	Species:	Drosophila melanogaster

Alignment Length:	205	Identity:	61/205 - (29%)
Similarity:	84/205 - (40%)	Gaps:	52/205 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PVIPPPNRPGR--------------RTNILEELKSVLNCLWRNR-FSYHFRHPVDSVSLGVPDYH 78
            |::|.|..|..              ||.:|..|:.    |:|.. .|..||:|||..:||:|||.
  Fly  1684 PLVPEPLAPNAGDKKKKCQFNPEELRTALLPTLEK----LYRQEPESVPFRYPVDPQALGIPDYF 1744

  Fly    79 AVVKHPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLMEAFYMRMES 143
            .:||.||||.|||..:.|..|....|.::|..|:|||..|||.:.|.||:....|.|.|
  Fly  1745 EIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSRVYRYCTKLSEVF------ 1803

  Fly   144 IDLSTEVELKPKSEKR----KRKATESLDQASTSFSAPRASNNYSRQWLSSSSSWLCPPPMPGGV 204
                 |.|:.|..:..    .||.|.:          |:....|.:|        ||..|.....
  Fly  1804 -----EAEIDPVMQALGYCCGRKYTFN----------PQVLCCYGKQ--------LCTIPRDAKY 1845

  Fly   205 SSFNPSFRNF 214
            .|:..|.:.:
  Fly  1846 YSYQNSLKEY 1855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_001369030.1	Bromodomain	39..143	CDD:413371	43/118 (36%)
tbrd-1	NP_001369030.1	Bromodomain	328..423	CDD:413371
nej	NP_001188575.1	ZnF_TAZ	530..600	CDD:214717
		KIX	946..1024	CDD:280354
		Bromo_cbp_like	1705..1812	CDD:99927	46/121 (38%)
		RING_CBP-p300	1824..1906	CDD:276805	8/50 (16%)
		PHD_CBP_p300	1908..1939	CDD:277032
		HAT_KAT11	1970..2283	CDD:285432
		ZZ_CBP	2339..2379	CDD:239077
		ZnF_TAZ	2404..2476	CDD:214717
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900