DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-1 and tbrd-2

DIOPT Version :9

Sequence 1:	NP_001369030.1	Gene:	tbrd-1 / 42823	FlyBaseID:	FBgn0039124	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_611401.2	Gene:	tbrd-2 / 37207	FlyBaseID:	FBgn0034423	Length:	674	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	106/442 - (23%)
Similarity:	167/442 - (37%)	Gaps:	112/442 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VQPPVIPPPNRPGRRTNILEELKS-VLNCLWRNRFSYHFRHPVDSVSLGVPDYHAVVKHPMDLST 89
            |||..||.|...||.||.|...|. :|:...:.:::..|..|||:.:|.||.|:.|:..|||:.|
  Fly    17 VQPEFIPHPGMAGRYTNKLHYFKKHLLDEARKKKYALDFLEPVDTEALMVPTYYTVIHRPMDIGT 81

  Fly    90 IRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLMEAFYMRMESIDLSTEVELK- 153
            |.||:.|.||...:||:.|||.|..||.|:|..|..||:.|::|.:.|:.::..:....||...
  Fly    82 IVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVYRKGQMLEKFFHKKLRGMPSGPEVPCNR 146

  Fly   154 ------------PKSEKRKRKATESLD--QASTSFSAPRASNNYSRQWLS----------SSSSW 194
                        |.|.:.:||..|.|.  |:.|:.:.....|.:|.:|.|          .|.:.
  Fly   147 DPKAVGRPRTNAPSSAQTERKCRELLKKLQSITNQTDAMTRNFFSNKWDSLQKKVDRQYFKSVNE 211

  Fly   195 LCPPPMPGGVSSFNPSFRNFVGPSLIPSFMPDSLVNP----MQSMHPMSSMMNPIFKNNWETNEA 255
            .|        ...:..||.:..|:.|   :.:.:.|.    ..||:..||:.:.:  |..:.||.
  Fly   212 FC--------LHVDGCFRKYHEPAKI---LYERVFNQPAAWCTSMNGNSSLESAL--NAADLNEL 263

  Fly   256 MDPPPSEPISYRPLDSLAAPLPSPPMEPMTLPWPTPAPVESPASSPPPAPNPPIIICYKSLDRMI 320
            :               .||.|....:...         |:.|.|..|......:.....:|::||
  Fly   264 L---------------AAAKLTVNSLMQC---------VQMPGSGEPLTAKSLVETFCDTLNKMI 304

  Fly   321 EKSHSDHLLKSMVKRKRKQVTWAFNQADYWRRYSQNPDYDHDREEKL-----------DWKILQE 374
                                    |:.:..:|.|.||  ...:.:|:           ::|...|
  Fly   305 ------------------------NKMEAGQRNSPNP--SSSKRQKMSPEQETDLVQGEFKPAME 343

  Fly   375 RL---DSDN-----FESFDGFVSSVRKMFQNALRCFPEDGLVKVSVKKTNEI 418
            .|   :.||     .||.|...........:|.||..:....|:......||
  Fly   344 LLSGNEIDNLMAVSIESSDDEAIDASMRITDADRCATQKLFAKLPTNAMKEI 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_001369030.1	Bromodomain	39..143	CDD:413371	41/104 (39%)
tbrd-1	NP_001369030.1	Bromodomain	328..423	CDD:413371	20/110 (18%)
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	38/101 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4352
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.950