Protein Alignment tbrd-1 and Brd3

DIOPT Version :10

• Sequence 1: NP_651190.1
• Gene: tbrd-1 / 42823
• FlyBaseID: FBgn0039124
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001421199.1
• Gene: Brd3 / 362092
• RGDID: 1308925
• Length: 742
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 136/515 - (26%)
• Similarity: 212/515 - (41%)
• Gaps: 130/515 - (25%)

  Fly    11 PPPRNEPYLQPVNGIVQPPVIPPPNRPGRRTNILEELKS-VLNCLWRNRFSYHFRHPVDSVSLGV 74
            |.|.|.|          ||.:..|::|||:||.|:.::: |:..||:::|::.|..|||::.|.:
  Rat    16 PGPVNPP----------PPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNL 70

  Fly    75 PDYHAVVKHPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLMEAFYM 139
            ||||.::|:|||:.||:|||.|.|||.|||.::||..:|.||.:||.....:....:.|.:.|..
  Rat    71 PDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQ 135

  Fly   140 RMESIDLSTEVELKPKSEKRK-RKATESLDQASTSFSAPRASNNYSRQWLSSSSSWLCPPPMPGG 203
            ::..:. ..||||.|.:.|.| ||            .|..|.|..::|.              |.
  Rat   136 KVAQMP-QEEVELLPPAPKGKGRK------------PAAGAQNAGAQQM--------------GA 173

  Fly   204 VSSFNPS--FRNFVGPSLIPSFMPDSLVNPMQSMHPMSSMMNPIFKNNWETNEAMDPPPSEPISY 266
            |||.:|:  |:|      ||         |..|..|:.: ..|:............|||:.|
  Rat   174 VSSVSPAPPFQN------IP---------PTVSQTPVIA-ATPVPTITANVTSVPVPPPAAP--- 219

  Fly   267 RPLDSLAAPLPSPPMEPMTLPWP------------------TPAPVESPASSPPPAPNP------ 307
                    |.|:.|:.|:..|.|                  |.|...|.:.||||...|
  Rat   220 --------PPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSEPKQAKVV 276

  Fly   308 --------PIIICYKSLD------------RMIEK-SHSDHLLKSMVKRKRKQVTWAFNQ---AD 348
                    ||....|.|:            ::.|. .|.|.:|:.|:.:|.....|.|.:   |:
  Rat   277 ARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAE 341

  Fly   349 YWRRYSQNPDYDHDREEKLDWKILQERLDSDNFESFDGFVSSVRKMFQNALRCFPEDGLVKVSVK 413
            ....:    ||....:..:|...::.::||..:....||.:.:|.||.|..:..|.|..|....:
  Rat   342 ALELH----DYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMAR 402

  Fly   414 KTNEIFEKR----------LPKYRELIATAKEKGRQLVASREQDFRDSQNLLIKQENANK 463
            |..::||.|          :|......|....||.:...|.|:...||.:...::|.|.:
  Rat   403 KLQDVFEMRFAKMPDEPMEVPALPAPTAPIVSKGAESSRSSEESSSDSGSSDSEEERATR 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_651190.1	Bromodomain	39..143	CDD:445827	42/104 (40%)
		Mucin15	139..>291	CDD:406167	36/172 (21%)
		Bromodomain	328..423	CDD:445827	24/107 (22%)
Brd3	NP_001421199.1	Bromo_Brdt_I_like	34..140	CDD:99929	42/105 (40%)
		Bromo_Brdt_II_like	311..412	CDD:99930	25/104 (24%)
		BET	588..652	CDD:435704