DRSC/TRiP Functional Genomics Resources

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Protein Alignment tbrd-1 and brdt

DIOPT Version :9

Sequence 1:NP_001369030.1 Gene:tbrd-1 / 42823 FlyBaseID:FBgn0039124 Length:513 Species:Drosophila melanogaster
Sequence 2:XP_002662470.2 Gene:brdt / 333996 ZFINID:ZDB-GENE-030131-5928 Length:1093 Species:Danio rerio


Alignment Length:469 Identity:119/469 - (25%)
Similarity:197/469 - (42%) Gaps:84/469 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 SNQPPPRNEPYLQPVNGIVQPPVIPPPNRPGRRTNILEEL-KSVLNCLWRNRFSYHFRHPVDSVS 71
            |:..||::    ..:||...||....|.:|||.||.|:.: |.|:..||::.||:.||.|||:|.
Zfish     2 SDVKPPQH----FTMNGNPPPPEFKNPKKPGRLTNHLQYIEKVVIRALWKHHFSWPFRQPVDAVR 62

  Fly    72 LGVPDYHAVVKHPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLMEA 136
            |.:|||:.::|:||||:||||||.|.|||:|.|.:|||..:|.||.:||..|..:....::|.:.
Zfish    63 LNLPDYYTIIKNPMDLTTIRKRLENNYYWKAMECVEDFNTMFTNCYVYNRPGDDIVLMAQVLEKL 127

  Fly   137 FY-----MRMESIDLSTEVELKPKSEKRKRKATESLDQASTSFSAPRASNNYSRQWLSSSSSWLC 196
            |.     |..|..::|......|  .|..||:|..|.:.                          
Zfish   128 FLEKVAEMPEEEYEISALTTKGP--VKGARKSTIGLKKR-------------------------- 164

  Fly   197 PPPMPGGVSSFNPSFRNFVGPSLIPSFMPDSLVNPMQSMHPMSSMMNPIFKNNWETNEAMDPPPS 261
             ||.|.....|..:.      ::||   ||:| :.:.|. |:|:.:....||..:.......|.:
Zfish   165 -PPSPMSEVVFQQTV------TVIP---PDAL-HTIPSA-PLSAQLTAKLKNGVKRKADTTTPSA 217

  Fly   262 EPISYRPLDSLAAPLPSPPMEPMTLPWPTPAPVESPASSPPPAPNPPIIICYKSLDRMIEKSHSD 326
            ..|   |....::.:..|.:..:.....:..|::.|....|.:|....:.....|...::  :.:
Zfish   218 SSI---PSCESSSCVTEPKVLKLFSRRGSGRPIKPPCKDLPESPPQHQVGRRTKLSERLK--YCN 277

  Fly   327 HLLKSMVKRKRKQVTWAFNQADYWRRYSQNP---------DYDHDREEKLDWKILQERLDSDNFE 382
            .:||.|..:|.....|.|          ..|         ||.....:.:|...:::::::..:.
Zfish   278 AILKEMFSKKHSAYAWPF----------YKPVDAETLGLLDYHEIIHQPMDMSTIKKKMEAREYT 332

  Fly   383 SFDGFVSSVRKMFQNALRCFPEDGLVKVSVKKTNEIFEKRL------PKYRELIAT----AKEKG 437
            ....|.:.:|.||.|..:..|....|....:|..::||.|.      ||....:::    .||:.
Zfish   333 DALQFAADMRLMFSNCYKYNPPGHEVVSMARKLQDVFEFRFSKIPDEPKNANPVSSHNRVKKERA 397

  Fly   438 RQLVASREQDFRDS 451
            |...:|...|...|
Zfish   398 RSPSSSESSDSESS 411

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tbrd-1NP_001369030.1 Bromodomain 39..143 CDD:413371 49/109 (45%)
Bromodomain 328..423 CDD:413371 20/103 (19%)
brdtXP_002662470.2 Bromo_Brdt_I_like 29..135 CDD:99929 48/105 (46%)
Bromo_Brdt_II_like 273..373 CDD:99930 20/111 (18%)
BET 514..577 CDD:293640
BRD4_CDT 1050..1093 CDD:293710
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000322
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100249
Panther 1 1.100 - - O PTHR22880
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
54.910

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