DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-1 and SPAC631.02

DIOPT Version :9

Sequence 1:	NP_001369030.1	Gene:	tbrd-1 / 42823	FlyBaseID:	FBgn0039124	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001342973.1	Gene:	SPAC631.02 / 2543426	PomBaseID:	SPAC631.02	Length:	727	Species:	Schizosaccharomyces pombe

Alignment Length:	497	Identity:	105/497 - (21%)
Similarity:	171/497 - (34%)	Gaps:	150/497 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SNSNQPPPRNEPYLQPVNGIVQ-PPVIPPPNRPGRRTNILEELKSVLNCLWRNRFSYHFRHPVDS 69
            |:.....|.:|...:..|...| ||:....::         .:.::|..|.|.|.|..||.|||.
pombe   205 SSKEHSSPHDETVKKEENDKDQYPPMTKEQHK---------YIHAMLRQLRRGRDSIPFRAPVDP 260

  Fly    70 VSLGVPDYHAVVKHPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLM 134
            |...:|||..::|:|:||.|::|:..:..|..|...::|..|:|.||.|||...|||...||.|.
pombe   261 VKQNIPDYPTIIKNPIDLGTMQKKFSSGVYSSAQHFIDDMNLMFSNCFLYNGTESPVGVMGKNLQ 325

  Fly   135 EAFYMRMESIDLSTEVELKPKSEKRKRKATESLDQASTSFSAPRASNNYS--RQWL--------- 188
            ..|..:::.:. |..|....:..:|.|..|.....|.|...|...||:.|  |:.:
pombe   326 ATFERQLKQLP-SAYVTSYSRPGRRPRSMTAPKGGARTRRQAAMYSNSSSGIRETMYDLKPHRRK 389

  Fly   189 SSSSSWLCPPPMPGGVSSFNPSFRNFVGPSLIPSFMPDSLVNPMQS---------MHPM--SSMM 242
            .::....|...:...:...:.::       ..|.:.|   |||...         .|||  .:|.
pombe   390 DAAEMKFCQSVLKELLKKQHEAY-------AYPFYKP---VNPTACGCPDYFKVIKHPMDLGTMQ 444

  Fly   243 NPIFKNNWETNEAMDPPPSEPISYRPLDSLAAPLPSPPMEPMTLPWPTPAPVESPASSPPPAPNP 307
            |.:..|.:.:.:|.:                        ..|.|.:.......|..:
pombe   445 NKLNHNEYASMKAFE------------------------ADMVLMFKNCYKFNSAGT-------- 477

  Fly   308 PIIICYKSLDRMIEKSHSDHLLKSMVKRKRKQVTWA----FNQADYWRRYSQNPDYDHDREEKLD 368
            |:.:..|.|:.:.:|                  .||    |:...|....|.|.||.:.
pombe   478 PVHLMGKKLESIFQK------------------LWANKPDFDSETYMGMSSVNTDYYYG------ 518

  Fly   369 WKILQERLDSDNFESFDGFVSSVRKMFQNALRCFPEDGLVKVSVKKTNEIFE---KRLPKYRELI 430
                    |::.|:|.|.|:.              :||          |.||   :::.|.:..:
pombe   519 --------DNEVFDSGDEFLE--------------DDG----------EEFEAVNRQIHKLQSTL 551

  Fly   431 ATAKEKGRQLVASREQDFR------------DSQNLLIKQEN 460
            ...|.:.|....||....|            :.||.|.:|.|
pombe   552 QAMKSRARSSSVSRRSRSRSLSVDIYPPITYEMQNELAEQCN 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_001369030.1	Bromodomain	39..143	CDD:413371	37/103 (36%)
tbrd-1	NP_001369030.1	Bromodomain	328..423	CDD:413371	18/101 (18%)
SPAC631.02	NP_001342973.1	COG5076	70..471	CDD:227408	71/309 (23%)
SPAC631.02	NP_001342973.1	BET	579..641	CDD:319097	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	1	1.000	-	-		mtm9289
orthoMCL	1	0.900	-	-		OOG6_100249
Panther	1	1.100	-	-	O	PTHR22880
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.860