Protein Alignment tbrd-1 and brdt

DIOPT Version :10

• Sequence 1: NP_651190.1
• Gene: tbrd-1 / 42823
• FlyBaseID: FBgn0039124
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: XP_012817895.2
• Gene: brdt / 100144959
• XenbaseID: XB-GENE-983868
• Length: 1013
• Species: Xenopus tropicalis
• Alignment Length: 477
• Identity: 127/477 - (26%)
• Similarity: 199/477 - (41%)
• Gaps: 83/477 - (17%)

  Fly    23 NGIVQPPVIPPP----NRPGRRTNILEEL-KSVLNCLWRNRFSYHFRHPVDSVSLGVPDYHAVVK 82
            :.||.||  ||.    .:.||.||.|:.| |.||..|||:.||:.|:.|||:..|.:|||:.::|
 Frog    10 SSIVNPP--PPEYINRKKTGRLTNQLQYLEKVVLKALWRHHFSWPFQQPVDAAKLNLPDYYQIIK 72

  Fly    83 HPMDLSTIRKRLHNKYYWQASEALEDFKLIFDNCLLYNLEGSPVYQAGKLLMEAFY-----MRME 142
            :|||||||||||...||.:|.:.::||..:|.||.:||..|..:....:.|.:.|.     |..|
 Frog    73 NPMDLSTIRKRLEYNYYSKALDCIQDFNTMFTNCYIYNKPGDDIVVMSQELEKVFMEKIAEMPHE 137

  Fly   143 SIDLSTEVELKPKSEKRKRKATESLDQASTSFSAPRASNNYSRQWLSSSSSWLCPPPMPGGVSSF 207
            .|:||.......|| :.|..|..:.:....|...|........|.: ...::.||      |.:.
 Frog   138 EIELSVVGNRGVKS-RIKISAVAAEESRDDSDYIPVCKKKMVSQKM-HRRTFPCP------VIAM 194

  Fly   208 NPSFRNFVGPSLIPSFMPDSLVNPMQSMHPMSSM--MNPIFKNNWETNEAMDPPPSEPISYRPLD 270
            .|.....|         |.|::....|.|..||:  :|...|...:|.             .|..
 Frog   195 MPKRTTLV---------PLSVIRSSTSSHSASSVSKVNKGIKRKADTT-------------TPAV 237

  Fly   271 SL-AAPLPSPPMEPMTLPWPTPAPV-------ESPASSPPPAPNPPIIICYKSLDRMIEK-SHSD 326
            || |....|.|    ||..|.|..:       .|..:|....|:....|.:...:::.|: .|.:
 Frog   238 SLIATSCESSP----TLSEPKPNKILSGTEKTRSAETSAVDLPDSQHHIHFIKSNQICEQLKHCN 298

  Fly   327 HLLKSMVKRKRKQVTWAFNQADYWRRYSQNP----DYDHDREEKLDWKILQERLDSDNFESFDGF 387
            ::|..|:.:|..:..|.|.:       :..|    |.....:..:|...:::::::..::....|
 Frog   299 NILNEMMSKKHAEYAWPFYK-------TVIPTSLLDCSDAIKHPMDLATIRDKMENGLYKDTQDF 356

  Fly   388 VSSVRKMFQNALRCFPEDGLVKVSVKKTNEIFEKRLPKYR----------ELIATAKEKGRQLVA 442
            .|.||.||.|:.:..|.|..|....:|..::||....|..          |...|:.|:.....:
 Frog   357 ASDVRLMFMNSYKYNPPDNEVVNMARKMQDVFEGMFAKIPDDPLATQSMVERYKTSTEESSSSSS 421

  Fly   443 SREQDFRDS-----QNLLIKQE 459
            |.:....||     |:|.:.||
 Frog   422 SEQSSSSDSEDERAQHLALLQE 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-1	NP_651190.1	Bromodomain	39..143	CDD:445827	47/109 (43%)
		Mucin15	139..>291	CDD:406167	35/154 (23%)
		Bromodomain	328..423	CDD:445827	21/98 (21%)
brdt	XP_012817895.2	Bromo_Brdt_I_like	28..134	CDD:99929	46/105 (44%)
		Bromodomain	293..392	CDD:445827	22/105 (21%)
		BET	526..589	CDD:435704
		BRD4_CDT	973..1013	CDD:465349