DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pli and peli1b

DIOPT Version :9

Sequence 1:	NP_001097890.1	Gene:	Pli / 42821	FlyBaseID:	FBgn0025574	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001071069.2	Gene:	peli1b / 558420	ZFINID:	ZDB-GENE-061027-372	Length:	425	Species:	Danio rerio

Alignment Length:	431	Identity:	241/431 - (55%)
Similarity:	309/431 - (71%)	Gaps:	27/431 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TDGTESPILAEDGGDGHDKPRLRYGELVILGYNGYLPQGDRGRRRSKFVLHKRTEASGVKRSKHY 69
            |..|:.|:              :||||::|||||.||.||||||:|:|.|.||.:::|||.|..:
Zfish    11 TSSTKVPV--------------KYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKSNGVKPSTVH 61

  Fly    70 IVQSPQTSKAILDANQHSISYTLSRNQAVIVEYKEDTETDMFQVGRSSESPIDFVVMDTLPGDK- 133
            :..:||.:|||.:.:||||||||||.|.|:|||.:|:.|||||:|||:||||||||.||:||.:
Zfish    62 VACTPQAAKAISNKDQHSISYTLSRVQTVVVEYTQDSNTDMFQIGRSTESPIDFVVTDTVPGSQS 126

  Fly   134 -KDAKVMQSTISRFACRILVNRCEPAKARIFAAGFDSSRNIFLGEKATKWQ-DNVEIDGLTTNGV 196
             .|.:.:|||||||||||:..|..|..|||:|||||||:||||||||.||: .:.::||||||||
Zfish   127 NSDTQSVQSTISRFACRIMCQRTPPYNARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGV 191

  Fly   197 LIMHPKGSFCGGNAKCGLWRECSVGGDVFSLRESRSAQQKGQPIYDECNILQDGTLIDLCGATLL 261
            |:|||:..|. .::|.|:|||.||.|:||:|||:|||||:|:.:.:|...|.||:||||||||||
Zfish   192 LVMHPRHGFT-EDSKPGVWREISVCGNVFTLRETRSAQQRGKMVENETQELVDGSLIDLCGATLL 255

  Fly   262 WRSAEGLQHSPTKHDLEKLIDAINAGRPQCPVGLNTLVIP--RKVNIGDQVNQPYVYLNCGHVQG 324
            ||:||||..:||...||.|...:||.|||||||.|||..|  |:.:|.|: .||:||||||||.|
Zfish   256 WRTAEGLSRTPTIKHLEALRQELNAARPQCPVGFNTLAFPSMRRKDIVDE-KQPWVYLNCGHVHG 319

  Fly   325 HHDWG-----QDENTG-ARRCPMCLELGPVVTLCMGLEPAFYVDVGAPTYAFNPCGHMATEKTVK 383
            :|:||     :|...| .|.||||...||.|.|.:|.|..||:|...||:||:||||:.:|||..
Zfish   320 YHNWGNRDAERDGREGRERECPMCRARGPYVPLWLGCEAGFYLDAAPPTHAFSPCGHVCSEKTAA 384

  Fly   384 YWANVEIPHGTNGFQAVCPFCATPLDGATGYIKLIFQDNLD 424
            ||:.:.:||||:.|.|.|||||..|:|..|||:||||..:|
Zfish   385 YWSQIPLPHGTHTFHAACPFCAQQLNGEQGYIRLIFQGPVD 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pli	NP_001097890.1	Pellino	21..424	CDD:398402	237/413 (57%)
peli1b	NP_001071069.2	Pellino	13..425	CDD:282553	239/427 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579317
Domainoid	1	1.000	492	1.000	Domainoid score	I356
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	492	1.000	Inparanoid score	I1370
OMA	1	1.010	-	-		QHG48577
OrthoDB	1	1.010	-	-		D251367at33208
OrthoFinder	1	1.000	-	-		FOG0001485
OrthoInspector	1	1.000	-	-		otm24641
orthoMCL	1	0.900	-	-		OOG6_104184
Panther	1	1.100	-	-	O	PTHR12098
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4716
SonicParanoid	1	1.000	-	-		X944
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.900