Protein Alignment Nup98-96 and NUP42

DIOPT Version :9

• Sequence 1: NP_001262885.1
• Gene: Nup98-96 / 42816
• FlyBaseID: FBgn0039120
• Length: 1960
• Species: Drosophila melanogaster
• Sequence 2: NP_010478.3
• Gene: NUP42 / 851774
• SGDID: S000002600
• Length: 430
• Species: Saccharomyces cerevisiae
• Alignment Length: 584
• Identity: 147/584 - (25%)
• Similarity: 190/584 - (32%)
• Gaps: 238/584 - (40%)

  Fly   132 MTAFGQ--TAAAQPTGSLFGQPAAATSTTGFGGFGTSAPTTTNVFGSGTASAFAQPQATAVGASG 194
            |:|||.  |:.|:|.         .::|:|...|..:|.:|.|:.|    |||.
Yeast     1 MSAFGNPFTSGAKPN---------LSNTSGINPFTNNAASTNNMGG----SAFG----------- 41

  Fly   195 VNTGTAVAKYQPTIGTDTLMKSGQANSVNTKQHCITAMKEFEGKSLEELRLEDYMCGRKGPQAGN 259
                      :|:.||...|..|...|
Yeast    42 ----------RPSFGTANTMTGGTTTS-------------------------------------- 58

  Fly   260 APGAFGFGAQVTQPAQPASGGLFGSTAQPSTGLFGQTVTENK-SMFGTTAFGQQ-------PATN 316
               |||         .|..|...|:|...|...||.|....| |.||..|||..       |:|.
Yeast    59 ---AFG---------MPQFGTNTGNTGNTSISAFGNTSNAAKPSAFGAPAFGSSAPINVNPPSTT 111

  Fly   317 NAFGAATQQNNFLQKPFGATTTTPFAAPAADASNPFGAKPAFGQGGSLFGQAPATSAAPAFGQTN 381
            :||||.:         ||   :|.|.|.|| .|||||..|  |..||.|||       ||||...
Yeast   112 SAFGAPS---------FG---STGFGAMAA-TSNPFGKSP--GSMGSAFGQ-------PAFGANK 154

  Fly   382 TGFGGFGTTAGATQQSTLFGATPAADPNKSAFGLGTAASAATTG-FGF-------GAPATSTAGG 438
            |.                ..::..::.|.||||..:.....||. ||.       .|.:||:|
Yeast   155 TA----------------IPSSSVSNSNNSAFGAASNTPLTTTSPFGSLQQNASQNASSTSSA-- 201

  Fly   439 GLFGNKPATSFAAPTFGATSTASTPFSNFGLNTSTAATGG----GLFN---------SGLNKPAT 490
                      |..|||||.:...:||... .||||::..|    |.|.         |.|...|.
Yeast   202 ----------FGKPTFGAATNTQSPFGTI-QNTSTSSGTGVSPFGTFGTNSNNKSPFSNLQSGAG 255

  Fly   491 SGFGGFGATSAAPLNFNAGNTGGSLFG--NTAKPGGGLFGGGTTTLGGTGAAPTGGLFGGGT--- 550
            :|...||.|::...|.|  |.|.|.||  |...|    |.||           :||.||..:
Yeast   256 AGSSPFGTTTSKANNNN--NVGSSAFGTTNNQSP----FSGG-----------SGGTFGSASNLN 303

  Fly   551 -TSFGGVGGSLGGGGFGMG-TNNSLTGGIMGAQPTLGIMTPSHQPIHQQILARVTSPYGDSPIFK 613
             .:.|....|.|..||..| |..:....:..:.|:.|...|:..|
Yeast   304 KNTNGNFQSSFGNKGFSFGITPQNDANKVSQSNPSFGQTMPNTDP-------------------- 348

  Fly   614 DLKLSSEADAT---------RATNPAAQQA-------------------VLDLTSNQYKISTSN 649
            ::.|.|..:||         .|||..|..|                   :.||.....||..:|
Yeast   349 NISLKSNGNATSFGFGQQQMNATNVNANTATGKIRFVQGLSSEKDGILELADLAEETLKIFRAN 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup98-96	NP_001262885.1	Nucleoporin_FG	395..481	CDD:316182	27/97 (28%)
		Nucleoporin2	888..1027	CDD:309287
		Nup96	1484..1762	CDD:314912
		Nucleoporin_FG	<1..74	CDD:316182
		Nucleoporin_FG	50..164	CDD:316182	9/33 (27%)
		Nucleoporin_FG	254..318	CDD:316182	20/71 (28%)
		NupH_GANP	316..>522	CDD:318883	71/228 (31%)
NUP42	NP_010478.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900