Protein Alignment Nup98-96 and SAR3

DIOPT Version :9

• Sequence 1: NP_001262885.1
• Gene: Nup98-96 / 42816
• FlyBaseID: FBgn0039120
• Length: 1960
• Species: Drosophila melanogaster
• Sequence 2: NP_178183.2
• Gene: SAR3 / 844407
• AraportID: AT1G80680
• Length: 1046
• Species: Arabidopsis thaliana
• Alignment Length: 1187
• Identity: 268/1187 - (22%)
• Similarity: 468/1187 - (39%)
• Gaps: 274/1187 - (23%)

  Fly   850 SNEAED-SAANQSRLAIEAAAAEAADDESHPTGIV-----LRRVGYYTIPSLDDL--RSYLAEDG 906
            |..|.| .:..:.|::::..||..    .|...|:     |....|:..|.:::|  |...:.|.
plant    13 SRMARDLDSRKKRRISLDGIAALC----EHSKEIIDSLPMLNSPDYFLKPCINELVEREIESPDY 73

  Fly   907 SCVVPNFTVGREGYGNVFFGKEMDVAGLNLDEIVHFRNKEIIIYPDDENKPPIGQGLNRDAQVTL 971
            ...||:||:||.|||.:.|....||..|:||.||.|...|:|:|.|:.:||.:|:|||:.|:|||
plant    74 CSRVPDFTIGRIGYGYIRFLGNTDVRRLDLDHIVKFHRHEVIVYDDESSKPVVGEGLNKAAEVTL 138

  Fly   972 -----DQVWPLDKTKHEAIKDPQRLLEMDWEGKLRRVCDKNDTRFIEYRPETGSWVFRVKHFSKY 1031
                 |..|...:..|.|.             ||::..::....||.:.|:.|.|.|.|.|||::
plant   139 VVNIPDLTWGKQQVNHIAY-------------KLKQSTERQGATFISFDPDNGLWKFFVPHFSRF 190

  Fly  1032 GLGDSDEE----DELP--TDP---KKAKIATLEAQQRANAEKMTLNSLRQAQKISEDAARNLDPK 1087
            ||.|.:.|    |:.|  .||   ...|:|.::.:.:....::.|:.       |..|...|||:
plant   191 GLSDDEAEDIAMDDAPGLGDPVGLDGKKVADIDEEDQMETSELELSH-------SLPAHLGLDPE 248

  Fly  1088 ALVAGVASGFRPMDDTAEFLLMDKTQFFQAGGNSDFSMFDPPRQRPTITSPTAVLAQEMVGNEAH 1152
                                                                             
plant   249 ----------------------------------------------------------------- 248

  Fly  1153 KMQLMKSSFFVEDNAPEDEPM-ETTGRLLRHRKFFNVEPLVWKDGASESSSQYDFEHPSPALPIS 1216
            ||:.|:...|..::..|.|.. |.|..|:......||.|       |:..:|.: .|..|. |:.
plant   249 KMKEMRMLMFPNEDEDESEDFREQTSHLMTSLTKRNVRP-------SQKIAQRN-SHQDPP-PVV 304

  Fly  1217 SSVSEASLMCDAHYEETSSMATGSIV-------AAVKETK---FEMPVTKAFKFVCKPKVAPIKL 1271
            .....|.|..:...:::|   .|||:       .||:::|   ||:.::         .|.|
plant   305 RKTPLALLEYNPGNDKSS---PGSILMVQQNKNLAVRKSKTGGFELDIS---------HVTP--- 354

  Fly  1272 RATTVPLPRSIAYEMRDNW---IADLGFYKGRSFKLSFGP--------------QNSLVLPSTYN 1319
                          :.||:   :.|...:.||||:..:||              .:.:||.|..|
plant   355 --------------LTDNYSRNVVDAALFMGRSFRAGWGPNGVLFHTGKPICSSSSQMVLSSVIN 405

  Fly  1320 NMQNLKEFTGPSLPVSMVFAPRSA---TDLSPSVMQL-----VEFNMVKGNEGFRESIIPHLEVQ 1376
                 ||    .:.:..|...|..   .:|..|..:.     .|.|.|:....|..     ..::
plant   406 -----KE----KIAIDKVVWDRKGKVQKELIDSAFEAPLSLHKELNHVEEEVRFGS-----FSLK 456

  Fly  1377 LNDCLSVNVEGSECPCIHPDSGTKLVSKHFSESLKQRNAGLKEDYSVSVWSLLFALW-------- 1433
            |.:.::..|..|:. |   .|...::.|....:....:|.|...:.|.||.|:..|:
plant   457 LQNVVTDRVVLSDI-C---RSYIGIIEKQLEVAGLSTSAKLFLMHQVMVWELIKVLFSERQSTER 517

  Fly  1434 -------GDHDELVDLEKNS-----HYMVMCRRNLLSEWLENTL---LGKDLLSKKVSTHSYLEH 1483
                   .:.|.:.|::::|     ..:.:.||...|.||:.::   :.:|:  ..::..|||||
plant   518 LMYAASDNEEDVMQDVKEDSAKIDTEALPLIRRAEFSCWLQESVSHRVQEDV--SDLNGSSYLEH 580

  Fly  1484 MLDLLSCHRVNEACELAFSYDDANLALVLSQLSSGAVFRLLMEEQLFAWQQSKSD-KYIDLERLK 1547
            :..||:...::.|.|||.|..|..||.:|||.....|.|..:.:||..|:::..| .:|:.||:|
plant   581 LFFLLTGRELDSAVELAISKGDVRLACLLSQAGGSTVNRNDILQQLHLWRRNGLDFNFIEKERIK 645

  Fly  1548 MYMLAAGAPMMQSSHGAINLLENKNWLTALALQLWYFTAPTSSITDALNAYNDAFQAEECYAEPP 1612
            :|.|.||     :.|.|:... ..:|...|.|.:|:...|.||:.....:|.  ....:..|..|
plant   646 LYELLAG-----NIHDALQDF-TIDWKRFLGLLMWHHLPPDSSLPIIFRSYQ--LLLNQAKAPWP 702

  Fly  1613 KPSYRD-APTD---TKKPVYDLRYHLLQLHSKRMHS---LEETLNPITHTADAMDFRLSWLLLQT 1670
            .|.|.| .|.|   :.....|:.|:|:.||||....   |:...:..:.|.|.:|:.:.|.....
plant   703 VPIYIDEGPADGFVSDNKHSDILYYLMLLHSKEEEEFGFLQTMFSAFSSTDDPLDYHMIWHHRGI 767

  Fly  1671 LRALGYRHCSPLTEARLSVDFASQLENEGLWQWGIFVLLHIKQQTQRERAVQQMLQRNVSVSAKV 1735
            |.|:|......|  ..|.:.|.:||.::||..|.|:|:|||..:....       ..:|:|..::
plant   768 LEAVGAFTSDDL--HTLDMGFVAQLLSQGLCHWAIYVVLHIPFREDHP-------YLHVTVIREI 823

  Fly  1736 AL-YAE-------ERFIVEELGIPMSWVDYAKAVKAGASGKHHLQAKYLLKAKHFATAHDVIFQH 1792
            .. |.|       :|..:::||||..|:..|.||.....|.........::..::..||.:....
plant   824 LFQYCETWSSMESQRQFIKDLGIPSEWMHEALAVYYNYHGDFVKALDQFIECANWQRAHSIFMTS 888

  Fly  1793 IAPDAIINGKMKYLHSLLIQFEDTEGSSIRVPNWANQGQIFLDFIDISAKFKQ-IRSVTNIADIN 1856
            :|....::.....:..:....:|.:.   .:.||.....|::.|..:.:..:: ..::..:..::
plant   889 VAHSLFLSANHSEIWRIATSMDDRKS---EIENWDLGAGIYMSFYLLKSSLQEDADTMVELEPLD 950

  Fly  1857 ARWENLKPQLSELCSRISL----LPCPTSKHRLCQSEISQSLSCLVHGMCIVCPEMESS-TVLKV 1916
            :..|:.:..:..|...:::    ||.   :.|:..|::::.:..|:.......|..|:. |..:.
plant   951 STNESCRNFVGRLNESLAVWGDRLPV---EARVAYSKMAEEICDLLLSDLSKNPSRETQLTCFET 1012

  Fly  1917 ALERLPLPQEFASKELR 1933
            |.: .|||::..|..|:
plant  1013 AFD-APLPEDVRSTHLQ 1028

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup98-96	NP_001262885.1	Nucleoporin_FG	395..481	CDD:316182
		Nucleoporin2	888..1027	CDD:309287	50/145 (34%)
		Nup96	1484..1762	CDD:314912	84/293 (29%)
		Nucleoporin_FG	<1..74	CDD:316182
		Nucleoporin_FG	50..164	CDD:316182
		Nucleoporin_FG	254..318	CDD:316182
		NupH_GANP	316..>522	CDD:318883
SAR3	NP_178183.2	Nucleoporin2	53..187	CDD:282016	50/146 (34%)
		Nup96	581..861	CDD:288926	85/296 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	109	1.000	Domainoid score	I2119
eggNOG	1	0.900	-	-		E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H35472
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D93359at2759
OrthoFinder	1	1.000	-	-		FOG0003622
OrthoInspector	1	1.000	-	-		otm2493
orthoMCL	1	0.900	-	-		OOG6_101756
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1810
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.720